Bit Octopus with Korean Language Support and Unique Technology, Shines as It Launches in the Korean Market, Leading a New Era of Crypto Trading SeaPRwire

Bit Octopus with Korean Language Support and Unique Technology, Shines as It Launches in the Korean Market, Leading a New Era of Crypto Trading

Hong Kong China – November 02, 2024 – (SeaPRwire) – On the global map of cryptocurrency markets, Bit Octopus (https://www.bitotop.com) is rapidly climbing onto the financial stage of Korea with the speed of lightning! As the industry’s first reverse copy-trading crypto trading platform, Bit Octopus not only provides investors with a secure and convenient trading environment but is also the center of attention for its unique reverse copy-trading technology and exceptional service. Expanding into a New Era The CEO of Bit Octopus has expressed their anticipation for the Korean market: “In this vibrant and innovative country, we see enormous potential. We are committed to bringing an unprecedented trading experience to Korean users.” Disruptive Technology and Features Revolutionary technology: Bit Octopus adopts cutting-edge artificial intelligence technology, ensured by its unique Proof of Transfer (PoX) consensus mechanism, allowing users to enjoy a trading experience that surpasses the market. Automated and reverse copy-trading: The advanced “BIT Sky Eye” system enables users to effortlessly implement intelligent trading and efficiently capture market opportunities. Ultimate security: Multi-layer data protection strategies provide an impregnable fortress for user assets. Localized Commitment and Support To better serve Korean users, Bit Octopus fully supports a Korean language interface and customer service. We will continue to optimize the trading experience to ensure users receive personalized services that meet local needs. Our goal, via meticulous market research and user feedback, is to ensure every Korean user enjoys dedicated trading support. Exclusive Launch Activities To celebrate the successful launch in Korea, Bit Octopus has introduced a series of attractive limited-time promotional activities. New users can receive free experience money for trading, as well as platform tokens Octopus Coin and other rich rewards. This means new users can get a certain amount of experience money right after registration, to try out various trading functions of the platform, while earning profits and accumulating practical experience at the same time. This is a risk-free opportunity to explore a market with huge potential. About Bit Octopus Founded in the fintech center of Hong Kong, Bit Octopus quickly rose to become a leading crypto trading platform with cutting-edge technology and a professional team. Our vision is to help investors increase wealth by providing innovative trading solutions. Our products cover a wide range, supporting diversified crypto asset trading, where users can experience: The most advanced technical support, ensuring the accuracy of market insights;Smooth and seamless trading operations, suitable from beginners to professional investors;Rich social interaction features, allowing users to grow together through sharing and learning. Furthermore, Bit Octopus continuously devotes itself to research and development and updates to ensure that the platform’s functions are constantly improved to adapt to the rapidly changing market environment, meeting the needs of all types of investors. To know more, please visit https://www.bitotop.com. The article is provided by a third-party content provider. SeaPRwire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Sectors: Top Story, Corporate News SeaPRwire provides real time press release distribution for companies and organizations to 6,500+ media outlets & 3.5 million professional desktops in 90 regions. It distributes press releases in different languages, including: IndonesiaFolk, IndoNewswire, SEATribune, IDNewsZone, LiveBerita, DailyBerita, TaiwanPR, SinchewBusiness, AsiaEase, BuzzHongKong, SingapuraNow, TIHongKong, TaipeiCool, TWZip, AsiaFeatured, dePresseNow, THNewson, KULPR, VNFeatured, MENAEntry, HunaTimes, DubaiLite, ArabicDir, BeritaDaring, TekanAsia, JamKopi ...
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Trump Kata Liz Cheney Mungkin Bukan ‘Helang Perang’ Jika Dia Ada Senjata Menunjuk Padanya berita

Trump Kata Liz Cheney Mungkin Bukan ‘Helang Perang’ Jika Dia Ada Senjata Menunjuk Padanya

(SeaPRwire) - GLENDALE, Ariz. — Donald Trump memanggil , salah seorang pengkritik Republikannya yang paling menonjol, seorang “elang perang” dan mencadangkan bahawa dia mungkin tidak akan begitu sanggup menghantar tentera untuk berperang jika dia sendiri yang diacukan senjata. Cheney membalas dengan menyifatkan calon presiden GOP itu sebagai “lelaki yang kejam, tidak stabil, dan ingin menjadi seorang tiran.” Pada sebuah acara lewat Khamis di Arizona, bersama bekas pengacara Fox News Tucker Carlson, Trump ditanya sama ada pelik melihat Cheney berkempen menentangnya. Bekas ahli kongres Wyoming itu secara terbuka menentang Trump sejak serangan ke atas Capitol AS pada 6 Januari 2021 dan telah menyokong Demokrat Kamala Harris dalam perlumbaan Rumah Putih, menyertai naib presiden itu pada beberapa perhentian baru-baru ini. Trump memanggil Cheney “orang yang gila” dan menambah, “Tetapi sebab dia tidak tahan dengan saya ialah dia selalu ingin berperang dengan orang. Kalau ikutkan dia, kita akan berada di 50 buah negara yang berbeza.” Bekas presiden itu meneruskan: “Dia adalah elang perang radikal. Mari kita letakkan dia dengan senapang di tangan, berdiri di sana dengan sembilan laras senjata yang diacukan padanya. OK, mari kita lihat bagaimana perasaannya. Anda tahu, apabila senjata itu diacukan ke wajahnya. “Anda tahu mereka semua elang perang apabila mereka duduk di Washington dalam sebuah bangunan yang bagus dan berkata, oh gee, mari kita hantar 10,000 tentera terus ke mulut musuh,” kata Trump. Cheney membalas pada Jumaat dalam catatan di X: “Beginilah cara diktator memusnahkan negara-negara bebas. Mereka mengancam mereka yang menentang mereka dengan kematian. Kita tidak boleh mempercayakan negara kita dan kebebasan kita kepada lelaki yang cetek, pendendam, kejam, dan tidak stabil yang ingin menjadi seorang tiran.” Terdahulu, selepas kempen Harris dan pengkritik Trump yang lain di media sosial melompat ke atas komennya, kempen Trump berkata dia “bercakap tentang bagaimana Liz Cheney ingin menghantar anak-anak lelaki dan perempuan Amerika untuk berperang dalam perang meskipun dia sendiri tidak pernah berada dalam perang.”Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Zink Baik Untuk Selesema? berita

Zink Baik Untuk Selesema?

(SeaPRwire) - Tidak ada ubat yang terbukti untuk selesema, tetapi ramai orang mempunyai yang mereka sumpah ketika mereka berasa tidak sihat. (Sup ayam atau buah sitrus, sesiapa?) Satu strategi biasa ialah mengambil tablet atau lozeng yang mengandungi zink, mineral semula jadi yang melawan bakteria dan virus. Tetapi ramai pakar tidak mengesyorkan agar orang ramai mengambil tablet zink sebaik sahaja mereka mengalami selesema. Dr. Katharine DeGeorge, doktor perubatan keluarga di University of Virginia yang mempunyai , adalah salah seorang daripada mereka. "Sesetengah orang mungkin mendapat manfaat," katanya. "Tetapi itu datang dengan kos—kos kewangan, dan juga risiko kejadian buruk." Pengguna zink memang mempunyai beberapa sains untuk menyokong keputusan mereka. bahawa zink boleh menghentikan virus selesema daripada berikatan dengan sel dalam badan dan menyalin dirinya sendiri, berpotensi memendekkan tempoh penyakit. (Sesetengah saintis sama ada zink mempunyai kesan yang sama terhadap virus lain, seperti virus yang menyebabkan selesema dan COVID-19, tetapi tidak banyak data untuk menyokong hipotesis itu, kata Dr. Roy Gulick, ketua penyakit berjangkit di Weill Cornell Medicine dan NewYork-Presbyterian.) Orang dewasa yang mula mengambil kira-kira 80 mg zink sehari dalam masa 24 jam selepas mendapat selesema berasa lebih baik dengan cepat daripada mereka yang tidak menggunakan zink, mencadangkan. Satu kajian baru-baru ini mengesahkan penemuan itu, berdasarkan analisis 34 kajian yang diterbitkan sebelum ini mengenai zink dan selesema. Penulis tidak menemui bukti bahawa mengambil zink secara proaktif boleh mencegah selesema, tetapi mereka menemui beberapa bukti bahawa mengambilnya ketika sakit mempercepatkan pemulihan kira-kira dua hari. Hari sakit yang lebih sedikit kedengaran hebat, kan? Tidak semestinya, kata Daryl Nault, profesor madya di Maryland University of Integrative Health dan pengarang bersama artikel ulasan Cochrane. Beliau dan rakan penyelidiknya menilai keputusan mereka sebagai "kepastian rendah" kerana kajian dalam ulasan itu berbeza-beza, meliputi bentuk dan dos zink yang berbeza dan direka dengan tahap kekukuhan saintifik yang berbeza. "Kita tidak benar-benar mempunyai bukti yang cukup untuk membuat kesimpulan muktamad daripadanya," katanya. "Paling baik, kita melihat bahawa mungkin ia boleh mengurangkan tempoh purata selesema selama beberapa hari." Tetapi, DeGeorge berkata, tidak semua orang mendapat manfaat daripada mengambil zink, dan ia sering menyebabkan kesan sampingan seperti perut tidak selesa, sakit kepala, dan rasa yang tidak enak. Mengambil zink dalam dos yang cukup tinggi untuk menjadi berkesan—kira-kira 80 mg sehari, menurut kajian mengenai subjek ini—meningkatkan kemungkinan mengalami simptom ini, katanya. "Pada satu tahap, anda menggantikan simptom selesema anda" dengan yang baru, kata Nault. Mungkin ada keadaan di mana berurusan dengan kesan sampingan itu berbaloi—jika anda mempunyai percutian yang akan datang dan ingin pulih sebelum anda bertolak, sebagai contoh. (Sebenarnya, Pusat Kawalan dan Pencegahan Penyakit A.S. sebagai alat berpotensi untuk pengembara.) Tetapi pada masa lain, katanya, anda mungkin sama baiknya dengan berdiam diri dan menanggung simptom selesema anda. Orang yang mengambil zink dalam dos yang sangat tinggi untuk tempoh masa yang lama juga boleh mengalami —termasuk masalah neurologi dan, secara ironinya, jatuh sakit lebih kerap. Mengambil produk yang dipasarkan untuk melegakan selesema untuk tempoh masa yang terhad yang anda alami simptom tidak seharusnya menjadikan anda berisiko mengalami komplikasi serius, kata DeGeorge, tetapi jangan berlebihan. Dan Mayo Clinic mengatakan untuk yang mengandungi zink, kerana ia boleh merosakkan deria bau anda. (Produk ini jarang berlaku, kerana Pentadbiran Makanan dan Dadah A.S. pada tahun 2009.) Memandangkan manfaat zink yang tidak pasti dan kekurangan yang berpotensi, Gulick berkata dia tidak selalu mengesyorkannya kepada pesakitnya. Orang yang ingin melegakan simptom mereka mungkin lebih baik menggunakan ubat-ubatan yang dijual bebas seperti dekongestan dan lozeng sakit tekak, katanya. DeGeorge juga berkata dia biasanya mengesyorkan agar orang ramai menjimatkan wang mereka dan mengelakkan kesan sampingan zink dengan memberi tumpuan kepada asas: tinggal di rumah, berehat secukupnya, dan minum banyak cecair. Selesema "akan hilang dengan sendirinya tidak kira apa yang anda lakukan," katanya. "Ia akan menyedihkan selama seminggu, tetapi tidak apa-apa."Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Announcement of the Launch of Toho Entertainment Asia Operations in Singapore SeaPRwire

Announcement of the Launch of Toho Entertainment Asia Operations in Singapore

Singapore – November 02, 2024 – (SeaPRwire) – Toho Co., Ltd. (hereinafter referred to as “the Company”) is pleased to announce that its subsidiary, Toho Entertainment Pte Ltd (hereinafter referred to as “TEA”), established in Singapore, and officially commenced operations on November 1, 2024. TEA will serve as a key base for the Company’s expansion into the Asian region, which is expected to see significant growth, focusing on IP and visual content licensing, product merchandising, marketing, and more. Background and Purpose of TEA’s Establishment Under our “TOHO VISION 2032” corporate strategy, the company has identified “Content & IP,” “International Expansion,” and “Animation” as its primary growth pillars. This vision aims to strengthen the creation and development of captivating content and IP while expanding business into international markets with significant growth potential. As part of this strategy, TEA was established in Singapore in February 2024, a hub for numerous Japanese companies, to act as a strategic base for expansion in the Asian market. Leveraging the expertise the Company has gained in Japan and North America, TEA will work to better understand the distinct needs and preferences of each market in Asia, allowing the Company to engage with audiences more deeply. Through this initiative, the Company aims to expand the licensing, merchandising, and other business opportunities of popular IPs such as Godzilla and TOHO Animation titles. Global Business Initiatives and Future Prospects To strengthen the global reach of key properties, such as Godzilla and TOHO Animation productions, In North America, Toho International, Inc. (hereinafter referred to as “TI”) has already made significant progress in expanding the Company’s business activities overseas. To enhance agility and responsiveness in decision-making and business development, the Company established Toho Global Inc. (hereinafter referred to as “TG”) as a separate entity in October 2023. TEA was subsequently founded as a TG subsidiary to lead the Company’s growth initiatives in Asia. The Company has also pursued M&A activities to strengthen its global presence, including investments in Thailand’s animation studio ‘IGLOO STUDIO’, U.S.-based streaming media production and distribution company ‘FIFTH SEASON’, and the acquisition of North American anime distributor ‘GKIDS’. Along with TG, the Company will continue to explore new global expansion opportunities beyond North America and Asia to support and accelerate its international business growth. “Our IPs and works, including Godzilla, have already gained significant recognition and popularity in various Asian markets outside of Japan. With the establishment of our local entity in Singapore, we aim to gain a deeper understanding of the specific needs of fans and the unique characteristics of each market. This will enable us to enhance engagement with our IPs and works. This initiative is part of our broader strategy to deepen our presence in markets where we have primarily focused on promotion in North America. Through this effort, we hope to bring even more joy to our audiences across Asia.” by Koji Ueda, CEO of TG. Details of TEA Location : Republic of Singapore Key Personnel: Koji Ueda (CEO), Fabio Murayama (Managing Director) Date of Establishment: February 29, 2024 Start of Operations: November 1, 2024 Shareholder: Toho Global Inc. Main Business Activities: Licensing of IP and visual content, marketing, merchandising business Contact Information TOHO Global Inc. Koji Ueda, k_ueda@toho.co.jp Takaaki Nakazawa, t_nakazawa@toho.co.jp The article is provided by a third-party content provider. SeaPRwire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Sectors: Top Story, Corporate News SeaPRwire provides real time press release distribution for companies and organizations to 6,500+ media outlets & 3.5 million professional desktops in 90 regions. It distributes press releases in different languages, including: IndonesiaFolk, IndoNewswire, SEATribune, IDNewsZone, LiveBerita, DailyBerita, TaiwanPR, SinchewBusiness, AsiaEase, BuzzHongKong, SingapuraNow, TIHongKong, TaipeiCool, TWZip, AsiaFeatured, dePresseNow, THNewson, KULPR, VNFeatured, MENAEntry, HunaTimes, DubaiLite, ArabicDir, BeritaDaring, TekanAsia, JamKopi ...
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Wakil dari Lebih 87 Negara Akan Menghadiri Simposium Antarabangsa ‘Mencipta Masa Depan’ berita

Wakil dari Lebih 87 Negara Akan Menghadiri Simposium Antarabangsa ‘Mencipta Masa Depan’

Simposium Antarabangsa "Mencipta Masa Depan" akan menghimpunkan penceramah, delegasi, artis, dan wartawan dari lebih 87 negara. Simposium ini adalah acara pertama yang dianjurkan oleh Pusat Kebangsaan "Rusia" atas arahan Presiden Persekutuan Rusia. Para ilmuwan, ahli falsafah, futuris ternama, penulis fiksyen sains terkenal, serta wakil dari sektor perniagaan dan industri kreatif dari Rusia, China, India, Itali, Iran, UAE, Kazakhstan, Serbia, Perancis, Amerika Syarikat, dan negara-negara lain telah mengesahkan penyertaan mereka dalam simposium ini. Simposium "Mencipta Masa Depan" dijangka mengumpulkan sekitar 3,000 peserta dari negara-negara anggota SCO, BRICS, CIS, dan negara-negara lain. Mereka akan membincangkan masa depan bumi, kesan teknologi ke atas masyarakat, peranan manusia dalam perkembangan tamadun, dan lebih penting lagi, rupa bentuk manusia pada masa depan. "Simposium Antarabangsa 'Mencipta Masa Depan' akan menjadi platform dialog antara para ilmuwan, penulis fiksyen sains, penggiat seni, wakil perniagaan, dan pegawai kerajaan. Bagi Pusat Kebangsaan 'Rusia', sangat bermakna bahawa acara pertamanya mendapat sambutan yang begitu besar. Wakil dari lebih 87 negara telah memberi maklum balas positif kepada inisiatif kami untuk membentuk masa depan bersama-sama. Kami sangat menghargai sokongan daripada Kementerian Luar Negeri Rusia dan semua yang terlibat dalam menjayakan acara penting ini," kata Tatiana Kareva, Ketua Pengurusan Kerjasama Antarabangsa Pusat Kebangsaan "Rusia". Peserta antarabangsa telah mula tiba di Rusia. Sebagai contoh, artis dari Brazil, Rafael Bteshe dan Monica Da Silva De Queiroz, serta Pengarah dan Timbalan Pengarah Sekolah Seni Halus dan Reka Bentuk Universiti Addis Ababa, Agegnehu Adane Dilnesahu dan Usman Hassan Mohammed, telah tiba di Moscow. Program lawatan khas di sekitar Moscow disediakan untuk mereka. Peserta simposium juga telah berkongsi harapan mereka terhadap acara ini. Wartawan penyiasatan Vesna Veizovich dari Serbia menyatakan: "Saya percaya Simposium Antarabangsa 'Mencipta Masa Depan' akan membuka ruang luas untuk bertukar-tukar idea tentang cara membina masyarakat yang bersedia menghadapi cabaran harian sambil mengekalkan nilai-nilai tradisional." John Molera, Pengarah Dasar dan Penyelidikan di DD Geopolitics dari Amerika Syarikat, menekankan: "Saya berharap dapat memperoleh inspirasi di simposium daripada orang di seluruh dunia yang membayangkan masa depan manusia di luar batas neoliberalisme Barat. Matlamat kami adalah untuk mencipta gerakan yang menghormati tradisi dan kepentingan, berdasarkan pengiktirafan dan kerjasama bersama." Pada 1 Julai 2024, Presiden Rusia Vladimir Putin menandatangani perintah untuk menubuhkan Pusat Kebangsaan "Rusia" bagi mengekalkan warisan Pameran "Rusia" dan menunjukkan pencapaian negara secara berterusan. Dari 4 hingga 6 November, Simposium Antarabangsa "Mencipta Masa Depan" akan diadakan di Pusat Kebangsaan "Rusia". Para peserta termasuk ilmuwan dan penyelidik, futuris dan peramal, penulis fiksyen sains, dan pegawai kerajaan. Simposium ini akan menjadi platform unik untuk dialog antarabangsa terbuka, di mana senario pembangunan manusia dan cabaran global moden akan dibincangkan. Program simposium merangkumi lebih 60 acara di bawah empat tema utama: masa depan manusia, masa depan teknologi, masa depan dunia multipolar, dan masa depan tamadun. Acara ini akan dihadiri oleh ilmuwan, futuris, wakil kerajaan, dan perniagaan dari lebih 40 negara, termasuk Austria, Argentina, India, China, UAE, Arab Saudi, dan banyak lagi. Jadual simposium telah diterbitkan di laman web rasmi — https://future.russia.ru/ dan siaran langsung acara akan tersedia di laman web tersebut sepanjang tempoh simposium. Sebagai sebahagian daripada pembukaan simposium, satu pameran akan dilancarkan untuk menyokong idea dialog tentang masa depan dunia yang berpusat pada manusia. Pameran ini akan membolehkan setiap pelawat menyedari kepentingan sumbangan peribadi dalam membentuk masa depan. Hubungi media: pressa@russia.ru Laman web Pusat Kebangsaan "Rusia" – https://russia.ru/ Laman web Simposium "Mencipta Masa Depan" – https://future.russia.ru/ Telegram: https://t.me/gowithRussia VK: https://vk.com/gowithrussia OK: https://ok.ru/gowithrussia
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Representatives from Over 87 Countries to Participate in the International Symposium “Creating the Future” SeaPRwire

Representatives from Over 87 Countries to Participate in the International Symposium “Creating the Future”

The International Symposium “Creating the Future” will gather speakers, delegates, artists, and journalists from more than 87 countries. The symposium marks the inaugural event of the National Center “Russia,” established by order of the President of the Russian Federation. Renowned scholars, philosophers, futurists, popular science fiction writers, business leaders, and representatives of the creative industries from Russia, China, India, Italy, Iran, the UAE, Kazakhstan, Serbia, France, the USA, and other nations have already confirmed their attendance at the symposium. The event will bring together approximately 3,000 participants from the SCO, BRICS, CIS, and other nations to discuss Earth’s future, the societal impact of technology, humanity’s role in civilization, and crucially, the concept of humanity’s future form. Tatiana Kareva, Head of the International Cooperation Department of the National Center “Russia,” highlighted, “The International Symposium ‘Creating the Future’ will serve as a platform for dialogue among scientists, science fiction writers, artists, business representatives, and government officials. It is very significant to the National Center ‘Russia’ that its inaugural event has sparked such keen interest. Representatives from over 87 countries have responded to our initiative to create the future together. We are grateful to the Russian Ministry of Foreign Affairs and to everyone assisting in holding this important event.” International participants have already started arriving in Russia. Among them are artists Rafael Btesh and Monica Da Silva De Queiroz from Brazil, as well as Agengue Adane Dilnesahu and Usman Hassan Mohammed, the director and deputy director of the School of Fine Arts and Design at Addis Ababa University. Special sightseeing programs around Moscow have been arranged for them. Symposium attendees have shared their expectations for the event as well. Investigative journalist Vesna Veizovic from Serbia remarked, “I believe that the International Symposium ‘Creating the Future’ will open up vast opportunities for exchanging ideas on shaping a society ready to face everyday challenges while preserving traditional values.” John Molera, Director of Policy and Research at DD Geopolitics from the United States, added, “I hope to find inspiration at the symposium from people worldwide who envision humanity’s future beyond Western neoliberalism. Our goal is to create a movement that respects traditions and interests, founded on mutual recognition and cooperation.” The International Symposium “Creating the Future” will be held from November 4 to 6 at the National Center “Russia,” with participants including scientists, researchers, futurists, forecasters, science fiction writers, and government officials. The symposium will offer a unique international platform for open dialogue on humanity’s development scenarios and contemporary global challenges. The program will feature over 60 events across four main themes: the Future of Humanity, the Future of Technology, the Future of a Multipolar World, and the Future of Civilization. Representatives from over 40 countries, including Austria, Argentina, India, China, the UAE, Saudi Arabia, and more, will participate. The symposium’s program is available on the website at https://future.russia.ru/, where live streams of the events will also be accessible during the symposium. The opening of the symposium will launch an exhibition focused on dialogue about humanity’s future, placing human beings at its center. This exhibition aims to help each visitor recognize the importance of their personal contribution to the future. Media Contact: pressa@russia.ruNational Center “Russia” website: https://russia.ru/Symposium “Creating the Future” website: https://future.russia.ru/Telegram: https://t.me/gowithRussiaVK: https://vk.com/gowithrussiaOK.ru: https://ok.ru/gowithrussia
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LeBron James Menyokong Kamala Harris, Mengutip Retorik Trump tentang Perlumbaan berita

LeBron James Menyokong Kamala Harris, Mengutip Retorik Trump tentang Perlumbaan

(SeaPRwire) - LeBron James, salah seorang paling popular di dunia, secara rasmi menyokong Naib Presiden Demokrat pada Khamis, menegur dalam video yang menyerlahkan retorik calon Republikan yang sering berapi-api mengenai kaum. “Ketika saya memikirkan anak-anak saya dan keluarga saya dan bagaimana mereka akan membesar, pilihannya jelas bagi saya. VOTE KAMALA HARRIS!!!,” tulis James di media sosial. Video yang sengit yang disertakan dengan catatan itu bermula dengan ucapan perkauman mengenai orang Amerika Hitam yang dibuat oleh seorang pelawak yang Trump platformkan di nya pada 27 Oktober, kurang dari dua minggu sebelum pilihan raya. Video selama satu minit dan 15 saat itu diselang-seli dengan Trump membuat komen yang memecah belahkan kaum dan disandingkan dengan gambar dari gerakan Hak Sivil Amerika Syarikat. Ia termasuk Trump mengatakan bahawa pendatang “meracuni darah negara kita” dan bahawa pendatang mengambil apa yang dipanggil “pekerjaan Hitam”. Gambar lain termasuk tajuk akhbar yang mengecam Trump atas bahasa yang dikatakan oleh pengkritik mencetuskan retorik Nazi atau perkauman yang berapi-api. Video itu berakhir dengan teks yang tertulis “benci membawa kita kembali”. Acara Trump di ditandai dengan bahasa misogynistic dan perkauman oleh sekutunya. Pelawak yang sama yang membuat komen mengenai orang Amerika Hitam di acara tersebut, Tony Hinchcliffe, juga menarik kecaman dwipartisan kerana memanggil Puerto Rico sebuah “.” Sokongan James dengan lima hari sebelum pilihan raya datang ketika Trump telah berusaha untuk mengurangkan kelebihan bersejarah Demokrat dengan minoriti, terutamanya lelaki Hitam dan Hispanik, tepat ketika Harris dan partinya telah memperdalam jangkauan. James, yang telah menggunakan platformnya yang terkenal untuk menimbang masuk dalam isu sosial dan budaya, telah berselisih dengan bekas Presiden Trump sebelum ini. Bintang NBA itu terkenal dengan label Trump sebagai “bum” kerana mengkritik pemain lain Stephen Curry dan selepas mereka kelihatan enggan melawat Rumah Putih ketika Trump sedang berkuasa seperti yang lazim untuk pasukan yang memenangi kejuaraan sukan. Presiden Trump ketika itu menarik balik undangan untuk pasukan tersebut dan mengkritik Warriors. “Kau @StephenCurry30 sudah berkata dia tidak akan pergi! Jadi oleh itu tidak ada undangan,” tulis James dalam (kemudian Twitter) pada tahun 2017. “Pergi ke Rumah Putih adalah penghormatan yang besar sehingga kau muncul!” LeBron juga mengecam Trump kerana mengkritik pemain NBA yang berlutut semasa dimainkan lagu kebangsaan Amerika Syarikat, dengan Republikan itu menggelarnya “memalukan” dan mengatakan bahawa dia mematikan permainan ketika dia melihat protes tersebut. “Saya benar-benar tidak fikir komuniti bola keranjang sedih kerana kehilangan penontonnya,” kata LeBron pada masa itu. Trump, seterusnya, juga mengkritik James, menghina kecerdasannya pada tahun 2018 dan menambah dalam catatan media sosial: “Saya suka Mike!” sebagai rujukan kepada legenda bola keranjang ikonik lain, Michael Jordan. James, bintang dan , secara meluas dianggap sebagai salah seorang pemain terhebat dari generasinya. Dia menyokong dan berkempen dengan Hillary Clinton pada tahun 2016, menyertai calon presiden Demokrat ketika itu pada acara kempen di Cleveland, dan juga memberikan sokongan kepada Presiden Joe Biden pada tahun 2020. Harris dalam tempoh menjelang Hari Pilihan Raya telah memanfaatkan sokongan sejumlah yang terkenal untuk meningkatkan daya tarikannya dan mencetuskan semangat di kalangan penyokong, termasuk bintang pop mega-star Beyoncé Knowles-Carter yang menyertainya pada perhimpunan di bandar halaman artis itu di Houston dan pemuzik rock Bruce Springsteen, antara lain. Seorang pegawai kempen kanan Harris, bercakap dengan syarat anonim semasa panggilan dengan wartawan pada Khamis, berkata sokongan selebriti menawarkan peluang kepadanya untuk berhubung dengan pengundi rendah kecenderungan di luar saluran politik biasa. Pegawai itu menambah bahawa beberapa tokoh awam telah menyokong Harris sendiri, walaupun kempen itu telah berusaha untuk menjalin hubungan dengan beberapa individu.Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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MWA Renews Learning and Development Contracts with Top Malaysian Institutions ACN Newswire

MWA Renews Learning and Development Contracts with Top Malaysian Institutions

KUALA LUMPUR, Oct 29, 2024 - (ACN Newswire via SeaPRwire.com) - Mogul Works Asia ("MWA"), a leading integrated marketing and talent solutions company in Southeast Asia, is proud to announce the renewal of its learning and development contracts with some of Malaysia's most renowned institutions. This marks a continuation of Mogul Works Asia's efforts to support local upskilling programs as part of the nation's strategy to cultivate a highly skilled and adaptable workforce.The renewed partnerships emphasize Mogul Works Asia's commitment to delivering high-quality learning and development solutions that cater to the needs of Malaysia's evolving economic landscape. Among the organizations that have extended their collaboration with Mogul Works are Khazanah Nasional, Touch 'n Go, CGC, Sime Darby, Sunway Group, Kenanga Investment Bank, and the Employees Provident Fund of Malaysia (KWSP), all of which are integral to Malaysia's growth plans.The founders of Mogul Works Asia, Mr. Lee John Salmon and Tunku Eddy Nasruan Adil, commented: "We are honored to continue our partnerships with these distinguished institutions. Our mission is to help build great people and companies here in Malaysia. We recognize the demand for Malaysian talent globally and aim to provide world-class training and opportunities to encourage that talent to develop within Malaysia."Over the years, Mogul Works Asia has focused on enabling these institutions and their diverse workforces to contribute meaningfully to both national development and regional and global competitiveness. This ongoing commitment positions the company as a key player in the talent development and marketing sectors, contributing to Malaysia's broader goal of establishing itself as a business hub in Southeast Asia.The renewal of these contracts not only strengthens Mogul Works Asia's foothold in the industry but also reflects the growing demand for trusted partners in learning and development, marketing, and employer branding. While specific contract details cannot be disclosed, standard project sizes for Mogul Works Asia range from USD 30,000 to over USD 1 million.Mogul Works Asia continues to support organizations in achieving their growth ambitions by combining specialized talent development, recruitment tools, and marketing expertise. With a focus on democratizing quality education, the company strives to build market leaders and enable more companies to grow their businesses in Malaysia. This is in line with Malaysia's goal of attracting, retaining, and cultivating talent within a rapidly evolving economy.Social LinksFacebook: https://www.facebook.com/mogulworksasia/Instagram: https://www.instagram.com/mogulworksasia/LinkedIn: https://www.linkedin.com/company/mogul-works-asia/tiktok: https://www.tiktok.com/@mogulworksasiaMedia ContactMogul Works AsiaAmalia MohdWebsite: https://www.mogulworks.asia Copyright 2024 ACN Newswire via SeaPRwire.com.
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Kisah Kontroversi Di Sebalik Siri Dokumen Baharu Netflix, The Manhattan Alien Abduction berita

Kisah Kontroversi Di Sebalik Siri Dokumen Baharu Netflix, The Manhattan Alien Abduction

(SeaPRwire) - Seperti kata pepatah terkenal, “Dua kemungkinan wujud: sama ada kita bersendirian dalam alam semesta ini atau kita tidak. Kedua-duanya sama menakutkan.” The Manhattan Alien Abduction meneroka kemungkinan kedua, tetapi akhirnya nampaknya cenderung kepada skeptisisme—sekurang-kurangnya dalam kes tertentu ini. Siri tiga bahagian ini, yang diketuai oleh Vivienne Perry dan Daniel Vernon, menyiasat dakwaan penculikan Linda Napolitano (dahulunya dikenali dengan nama samaran Linda Cortile), seorang suri rumah di Bandar Raya New York yang mendakwa bahawa pada awal pagi 30 November 1989, tiga makhluk asing menculiknya dari apartmen tingkat 12nya di tengah bandar, membawanya melalui langit ke kapal angkasa mereka, dan menjalankan eksperimen ke atasnya sebelum mengembalikannya ke bilik tidurnya. Kes ini sebelum ini didokumentasikan dari sudut pandangan seorang yang mempercayai dalam buku yang diterbitkan pada tahun 1997 oleh arwah pengarang Budd Hopkins, seorang ahli ufologi yang terkenal yang mempunyai hubungan rapat dengan Napolitano sebelum kematiannya pada tahun 2011. Walau bagaimanapun, bukti yang dikatakan dikemukakan dalam Witnessed untuk menyokong dakwaan Napolitano dipertikaikan dalam The Manhattan Alien Abduction oleh arwah bekas isteri Hopkins, Carol Rainey, seorang pembuat filem yang mendokumentasikan penerokaan suaminya terhadap pengalaman Napolitano. Rainey menceritakan kisahnya sendiri—yang merupakan bahawa semuanya adalah satu tipu daya yang rumit yang dirancang oleh Napolitano—kepada Netflix sebelum kematiannya pada tahun 2023. Siri dokumentari ini banyak bergantung pada temu bual dengan Napolitano, yang kini berusia 77 tahun, dan Rainey—yang jelas-jelas mempunyai hubungan yang perbalahan antara satu sama lain—serta rakaman yang belum pernah dilihat sebelum ini yang dirakam oleh Rainey, dan lakonan semula yang dramatik untuk membina semula peristiwa yang berlaku sekitar dakwaan penculikan dan kesudahannya. Kisah Napolitano juga telah didokumentasikan dalam podcast pada tahun 2018 dan dokumentari Apple TV+ pada tahun 2022 The Alien Abduction Case of the Century: The Linda Napolitano Story. Apakah yang dikatakan berlaku kepada Linda Napolitano? Pada bulan April sebelum dakwaan penculikannya pada November 1989, Napolitano menghantar surat kepada Hopkins yang menggambarkan pertemuan makhluk asing sebelumnya yang dia dakwa telah alami pada hujung minggu di Catskills 13 tahun sebelumnya. Tidak lama selepas itu, dia mula menghadiri mesyuarat kumpulan sokongan Hopkins untuk mangsa penculikan. Selepas pertemuan pertama ini, Napolitano mendakwa bahawa dia telah menemui benjolan aneh di tepi hidungnya yang, apabila di-X-ray, telah dikatakan mendedahkan objek asing yang kecil. Hopkins menganggap ini sebagai bukti bahawa makhluk asing telah memasukkan implan ke dalam hidungnya dan merujuknya sebagai "senjata merokok radiologi." Tetapi objek itu dikatakan telah hilang apabila seorang pakar kemudiannya cuba mengeluarkannya. Berikutan insiden November 1989, inti kes Hopkins untuk menyokong dakwaan Napolitano terletak pada penegasan bahawa 23 orang dikatakan telah tampil dan mengatakan bahawa mereka telah menyaksikan dia terapung di langit Manhattan. “Jika saya berhalusinasi,” kata Napolitano kepada pada tahun 2013, “maka saksi-saksi melihat halusinasi saya. Itu kedengaran lebih gila daripada keseluruhan fenomena penculikan.” Walau bagaimanapun, identiti mana-mana saksi tidak pernah disahkan dan tidak ada bukti konkrit bahawa dua lelaki yang memberikan keterangan yang paling meyakinkan—pegawai keselamatan yang dikatakan bernama Richard dan Dan yang dikatakan sedang meletak kereta di dekat sana menjaga Setiausaha Agung PBB ketika itu, Javier Pérez de Cuéllar—malah wujud kerana mereka berkomunikasi secara eksklusif dengan Hopkins melalui surat. Cuéllar kemudiannya memberikan di mana dia menolak sebarang dakwaan bahawa dia terlibat dalam insiden tersebut. “Saya tidak dapat tetapi menafikan dengan tegas dakwaan bahawa saya telah mengalami penculikan pada bila-bila masa,” tulisnya. “Pada beberapa kesempatan, apabila ditanya mengenai perkara tersebut, saya mengulangi bahawa tuduhan ini sama sekali tidak benar dan saya berharap kenyataan ini akan menamatkan khabar angin yang tidak berasas ini.” Beberapa rakaman Rainey yang dimasukkan dalam siri ini juga menunjukkan bahawa keterangan saksi mengenai apa yang dikatakan mereka lihat pada malam itu sangat berbeza, dengan seorang wanita mendakwa dia hanya melihat cahaya terang melalui langsirnya. Rainey terus mengkritik Hopkins kerana gagal menghiraukan unsur-unsur yang menjatuhkan kredibiliti kes tersebut. “Budd memilih butiran yang meyakinkan tetapi mengabaikan apa sahaja yang menimbulkan pertanyaan yang sukar,” katanya. Apakah kebenarannya? Pada akhirnya, terpulang kepada penonton untuk memutuskan siapa dan apa yang mereka percayai. Tetapi Napolitano telah menyatakan dengan jelas bahawa dia tidak bersetuju dengan penggambarannya dalam siri ini. Menjelang tayangan sulungnya pada 30 Oktober, dalam percubaan untuk menghentikan tayangan projek tersebut. Menurut aduannya, yang difailkan di Mahkamah Agung Negeri New York pada hari Isnin, dokumentari itu memfitnah Napolitano dan melukiskannya dalam cahaya yang tidak menarik sementara membenarkan Rainey memainkan peranan penting dalam cerita itu sebagai "ahli skeptik' dalam bidang ini" sedangkan dia sebaliknya adalah "bekas isteri yang marah dan mabuk yang bertekad untuk membalas dendam terhadap suaminya." Saman itu mendakwa dokumentari itu adalah "tindakan terakhir Rainey untuk membalas dendam terhadap bekas suaminya, daripada mempamerkan kebenaran sebenar seperti yang disiasat dan ditulis... dalam Witnessed." Memandangkan The Manhattan Alien Abduction telah ditayangkan, nampaknya seorang hakim tidak mengabulkan permintaan Napolitano untuk menghalang Netflix daripada menayangkan siri ini. Netflix tidak segera memberi respons kepada permintaan TIME untuk komen mengenai saman itu.Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Eisai Completes Rolling Submission to US FDA for LEQEMBI(R) (lecanemab-irmb) Biologics License Application for Subcutaneous Maintenance Dosing for the Treatment of Early Alzheimer’s Disease Under the Fast Track Status JCN Newswire

Eisai Completes Rolling Submission to US FDA for LEQEMBI(R) (lecanemab-irmb) Biologics License Application for Subcutaneous Maintenance Dosing for the Treatment of Early Alzheimer’s Disease Under the Fast Track Status

TOKYO and CAMBRIDGE, Mass., Nov 1, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Biogen Inc. announced today that Eisai has completed the rolling submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for lecanemab-irmb (U.S. brand name: LEQEMBI®) subcutaneous autoinjector for weekly maintenance dosing after it was granted Fast Track designation by the FDA. LEQEMBI is indicated for the treatment of Alzheimer’s disease (AD) in patients with Mild Cognitive Impairment (MCI) or mild dementia stage of disease (collectively referred to as early AD). If the FDA accepts the BLA, the Prescription Drug User Fee Act (PDUFA) action date (target date for completion of examination) will be set.The BLA is based on data from the Clarity AD (Study 301) open-label extension (OLE) and modeling of observed data. If approved by the FDA, the LEQEMBI autoinjector could be used to administer LEQEMBI at home or at medical facilities, and the injection process is expected on average to take about 15 seconds. As part of the subcutaneous autoinjector 360 mg weekly maintenance regimen under review, patients who have completed the biweekly intravenous (IV) initiation phase would receive weekly doses that maintain effective drug concentrations to sustain the clearance of highly toxic protofibrils* which can continue to cause neuronal injury even after the amyloid-beta (Aβ) plaque has been cleared from the brain.AD is an ongoing neurotoxic process that begins before and continues after plaque deposition. Data suggest that early and continuing treatment may prolong the benefit of therapy even after plaque is cleared from the brain. This SC autoinjector is expected to be easier for patients and their care partners to use and may reduce the need for hospital or infusion site visits and nursing care compared to IV administration. In addition to potentially maintaining the clinical and biomarker benefits, subcutaneous maintenance dosing may be more convenient for patients and their care partners to continue the treatment.LEQEMBI is approved in the U.S., Japan, China, South Korea, Hong Kong, Israel, UAE and Great Britain. Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union (EU). The US FDA accepted Eisai’s Supplemental Biologics License Application (sBLA) for monthly LEQEMBI IV maintenance dosing in June 2024 and set a PDUFA action date for January 25, 2025.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority.* Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition.1 Protofibrils cause injury to neurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.2INDICATIONLEQEMBI® [(lecanemab-irmb) 100 mg/mL injection for intravenous use] is indicated for the treatment of Alzheimer’s disease (AD). Treatment with LEQEMBI should be initiated in patients with mild cognitive impairment (MCI) or mild dementia stage of disease, the population in which treatment was initiated in clinical trials.For the full press release, visit https://www.eisai.com/news/2024/news202482.html. About lecanemab (LEQEMBI®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab is approved in the U.S.,3 Japan,4 China,5 South Korea,6 Hong Kong,7 Israel,8 the United Arab Emirates9 and Great Britain.10 Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union (EU).LEQEMBI’s approvals in these countries was based on Phase 3 data from Eisai’s, global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results. The primary endpoint was the global cognitive and functional scale, Clinical Dementia Rating Sum of Boxes (CDR-SB). In the Clarity AD clinical trial, treatment with lecanemab reduced clinical decline on CDR-SB by 27% at 18 months compared to placebo.11,12 The mean CDR-SB score at baseline was approximately 3.2 in both groups. The adjusted least-squares mean change from baseline at 18 months was 1.21 with lecanemab and 1.66 with placebo (difference, −0.45; 95% confidence interval [CI], −0.67 to −0.23; P
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Fujitsu and AMD to begin strategic partnership to develop more sustainable computing infrastructure intended to accelerate open-source AI initiatives JCN Newswire

Fujitsu and AMD to begin strategic partnership to develop more sustainable computing infrastructure intended to accelerate open-source AI initiatives

Kawasaki, Japan and Santa Clara, California, Nov 1, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu and AMD (NASDAQ: AMD) today announced that they have signed a memorandum of understanding (MOU) to form a strategic partnership to create computing platforms for AI and high-performance computing (HPC). The partnership, encompassing all aspects from technology development to commercialization, will seek to facilitate the creation of open source and energy efficient platforms comprised of advanced processors with superior power performance and highly flexible AI/HPC software and aims to accelerate open-source AI and/or HPC initiatives.Due to the rapid spread of AI, including generative AI, cloud service providers and end-users are seeking optimized architectures at various price points and power per performance configurations. From end-to-end, AMD supports an open ecosystem, and strongly believes in giving customers choice. Fujitsu has worked to develop FUJITSU-MONAKA (1), a next-generation Arm-based processor that aims to achieve both high performance and low power consumption. With FUJITSU-MONAKA, together with AMD Instinct™ accelerators, customers have an additional choice to achieve large-scale AI workload processing to whilst attempting to reduce the data center total cost of ownership.This collaboration will focus on the three strategic areas of engineering, ecosystems, and business, bringing together Fujitsu’s world-leading supercomputer-based advanced CPU technology with industry-leading AMD GPU technology. Under this collaboration, Fujitsu and AMD will target joint development of innovative computing platforms for AI and HPC by 2027.In addition, based on AMD ROCm™ software, an open-source AI/HPC software stack for GPUs, and Fujitsu’s Arm-based FUJITSU-MONAKA software, Fujitsu and AMD will enhance their collaboration with the open-source community. Both companies seek to advance the development of open-source AI software that is optimized for the AI computing platforms they will provide, and work to expand the ecosystem.Fujitsu and AMD will also collaborate on marketing and co-creation with customers to offer these AI computing platforms globally. In addition, to expand AI use cases and promote the societal implementation of AI, based on the computing infrastructure of FUJITSU-MONAKA and AMD Instinct accelerators, both companies will collaborate to build an open and more sustainable AI/HPC platform ecosystem, including a joint customer center.Through this collaboration, Fujitsu and AMD are bringing their respective world-leading technologies together and will promote open-source AI initiatives by offering more sustainable options in both hardware and software that can be utilized by many companies.Vivek Mahajan, Corporate Vice President, CTO, CPO, Fujitsu Limited, comments:“Through this strategic partnership with AMD, Fujitsu seeks to accelerate open-source AI initiatives with a shared vision of achieving sustainable computing platforms. By combining AMD’s innovative GPU technology with Fujitsu’s low-power/high-performance processor FUJITSU-MONAKA, we seek to create an environment in which more companies will be able to utilize AI while reducing the power consumed by data centers. I believe that this partnership is an important step forward in accelerating Fujitsu’s efforts to achieve a sustainable society.”Phil Guido, EVP, Executive Vice President and Chief Commercial Officer, AMD comments:"By combining our cutting-edge AMD Instinct™ accelerators with Fujitsu’s advanced low-power processors, we are positioned to deliver high-performance and energy-efficient solutions that will benefit our joint AI and HPC customers. Our strategic partnership with Fujitsu not only underscores our commitment to innovation but also highlights our dedication to Japan, where we recognize the importance of local partnerships and expertise. As we continue to expand our relationships in Japan, we are excited about the opportunities to create a more sustainable computing infrastructure that aligns with Japan's technological leadership and commitment to sustainability."(1) FUJITSU-MONAKA :A processor based on the ARM instruction set architecture, employing cutting-edge 2-nanometer technology. It achieves high performance through utilizing Fujitsu’s proprietary many-core architecture for high performance and low power consumption. In addition, by supporting industry standard software through Fujitsu’s collaboration with the open-source community, FUJITSU-MONAKA promotes building an environment in which it is easy to maximize performance. This new technology applied to the FUJITSU-MONAKA is based on results obtained from a project subsidized by the New Energy and Industrial Technology Development Organization (NEDO).About AMDFor more than 50 years AMD has driven innovation in high-performance computing, graphics, and visualization technologies. Billions of people, leading Fortune 500 businesses, and cutting-edge scientific research institutions around the world rely on AMD technology daily to improve how they live, work, and play. AMD employees are focused on building leadership high-performance and adaptive products that push the boundaries of what is possible. For more information about how AMD is enabling today and inspiring tomorrow, visit the AMD (NASDAQ: AMD) website, blog, LinkedIn and X pages.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiriesAMD PR agency, Burson JapanE-mail: AMDPR@bcw-global.com Copyright 2024 JCN Newswire via SeaPRwire.com.
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Standard Uranium Provides Exploration Update Highlighting Successful Project Generation with New Joint Venture Ready Projects Available in 2025 ACN Newswire

Standard Uranium Provides Exploration Update Highlighting Successful Project Generation with New Joint Venture Ready Projects Available in 2025

Vancouver, British Columbia--(ACN Newswire via SeaPRwire.com - October 31, 2024) - Standard Uranium Ltd. (TSXV: STND) (OTCQB: STTDF) (FSE: 9SU0) ("Standard Uranium" or the "Company")is pleased to provide a summary of work programs on three of it's 100% owned uranium exploration projects currently under option and plans for targeted exploration strategies to continue advancing its uranium portfolio in the Athabasca Basin region, northern Saskatchewan towards discovery.The Company holds more than 233,000 acres of prime exploration real estate across the prolific Athabasca Basin region, which hosts the highest-grade uranium deposits on the planet. The Company boasts an attractive portfolio of uranium exploration projects currently available for option ranging from early-stage to drill-ready projects throughout the Athabasca region, providing turn-key opportunities with permits in hand, First Nations agreements signed, vendors secured, and highly prospective uranium targets. Standard Uranium has continued to deliver on its project generator model in 2024 through expansion of landholdings and advancement of early-stage projects through geophysical surveys to be executed this fall, providing excellent turn-key opportunities for potential joint venture partners. The Company is actively seeking new joint venture partners on these exciting uranium projects.Additionally, the Company successfully completed three joint venture earn-in partnerships on the Sun Dog, Canary, and Atlantic projects this year, totalling over $23.8M in work commitments over the next three years. The Company advanced all three projects by successfully operating and completing exploration drill programs on time and under budget. Standard Uranium brings a skilled team of in-house geoscientists and invaluable relationships with First Nations partners and vendors to the table in designing and executing option agreements.2024 Exploration Summary and ObjectivesProject Generator: Completed four definitive option agreements on four projects, securing exploration expenditures and non-dilutive cash-flow into the Company - Sun Dog, Atlantic, Canary, and Brown Lake projects.Aggressive Exploration: Successfully planned and operated three drill programs on Sun Dog, Atlantic, and Canary returning promising results of uranium mineralization and prospective geology, all of which were partner-funded and successfully operated by the Company.Additional Project Advancement: Initial exploration and geophysical programs on the early-stage Rocas and Corvo projects is planned for the fall, creating more opportunities for additional option partnerships.Expanded Landholdings: The Company added nearly 45,000 acres of prospective land to its portfolio in 2024 through low-cost staking, expanding the Ascent and Corvo projects significantly, and adding four new projects to its exploration pipeline in the Athabasca Basin region."We are pleased to share that we are continuing to advance additional uranium exploration projects through targeted geophysical survey work and new staking, which provide more opportunities for new joint venture partners looking to enter the Athabasca Basin. This part of our business represents an outstanding opportunity for companies that want to explore in the world's best uranium jurisdiction with our team at Standard Uranium," said Jon Bey, CEO & Chair of Standard Uranium. "We have built strong relationships with government and our First Nations partners allowing for expediting permitting, along with the key vendors to ensure exploration projects are completed on time and on budget." Figure 1. Overview of the eastern Athabasca Basin region highlighting Standard Uranium's projects under option and available for JV.To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10633/228449_c6974358c4f45b18_002full.jpgEastern Athabasca Basin Exploration Highlights & OpportunitiesAtlantic Project - ATCO Mining Option (CSE: ATCM)Uranium Mineralization Confirmed: Analytical results from the winter 2024 drill program at the Project confirmed highly anomalous uranium in drill holes ATL-24-002, ATL-24-004A, and ATL-24-005A, coinciding with prospective structural zones and favorable alteration including dravite-rich clays.Sandstone & Basement-Hosted Uranium: Multiple zones of elevated uranium linked to the sub-Athabasca unconformity and basement structural zones were intersected, indicating a uranium-fertile system.Uranium Pathfinders: Several key uranium pathfinder elements are present in anomalous quantities in multiple drill holes, providing vectoring information for future programs. Intersections of dravitic-clay associated with structural zones has been confirmed in drill holes ATL-24-002, ATL-24-004A, and ATL-24-005A.Verified Targets: Massive structural disruption confirmed in the sandstone column and multiple wide (>10 metres) brittle-reactivated graphitic shear zones confirm the main interpreted electromagnetic ("EM") corridor on the western claim block which was not reached by previous operators. The inaugural program results have confirmed the Company's exploration thesis on the Project, highlighting a uranium-fertile system with several kilometres of still untested strike length across the Project.Follow Up Targets & Next Steps: Atlantic holds significant upside for discovery along the untested portions of the E-W conductor system. Supplementary geophysical surveys over the central claim blocks are currently being planned and will provide further target areas for phase II and III drilling, along with the additional untested gravity low anomalies on the western block identified in 2022.Canary Project - Mamba Exploration Option (ASX: M24)Uranium Mineralization Confirmed: Analytical results from the spring 2024 drill program at the Project confirmed moderately anomalous uranium in drill holes CAN-24-001 and CAN-24-003 with Uranium:Thorium ("U:Th") ratios ≥3:1, indicating hydrothermal uranium input.Basement-Hosted Uranium: Multiple zones of elevated uranium linked to structural zones and/or proximal to lithological contacts, indicating a uranium-fertile system.Elevated Uranium Pathfinders: Several key uranium pathfinder elements are present in anomalous quantities in multiple drill holes within the crystalline basement, providing vectoring information for future programs; anomalous Boron is particularly common. Spectroscopy confirms presence of fracture-hosted dravitic-clay (13.4%) associated with semi-pelitic gneiss in drill hole CAN-24-001.Follow Up Targets & Next Steps: Canary holds significant upside for discovery along three different and significantly underexplored conductor systems. Supplementary geophysical surveys over all three corridors will provide further target areas for phase II and III drilling.Brown Lake - Mustang Energy Acquisition Agreement (CSE: MEC)Project Monetization: Acquired in 2023 via low-cost staking, Standard Uranium sold 90% of the 312-hectare Brown Lake project to Mustang Energy for 60,000 common shares in Mustang and retains a 10% free carried interest in the project, providing future discovery upside potential.Shallow drill targets: 300 counts per second ("cps") were intersected in seven of eight drill holes - Geochemical assays still pending.Prospectivity Model Confirmed: Elevated radioactivity and increased hydrothermal alteration at Wishbone are largely associated with stacked graphitic structural zones, indicating favorable corridors for fluid movement and uranium deposition across the Project akin to other basement-hosted Athabasca deposits.Discovery of Radioactivity: Occurrences of strong to intense radioactivity in outcropping graphitic basement rocks were identified at surface while prospecting at the Wishbone target area:Approximately five kilometres of strike length along a regional scale anticline, defined by strong VTEM conductors with associated radioactivity along each fold limb.Graphitic pelites have been mapped along both fold limbs, hosting strong radioactivity up to 22,300 cps (RS-125 handheld scintillometer).Mineralized cross-cutting faults have been mapped in the overlying rocks which intersect the uranium-bearing graphitic pelite unit.Historical outcrop sampling at the northwestern graphitic pelite exposure returned assay results of 0.32% U3O8 and 0.30% Cu (SMDI #2095).Unrealized Potential: The targets tested during the summer 2024 program represent only a small fraction of the dozens on the ground and the Company is working with its option partners to prioritize follow ups for additional geophysics and drill programs to further test these promising areas.Davidson River Project - Flagship ProjectIn 2023, the Company expanded its flagship Davidson River project in the southwest corner of the Basin to cover more than 37,700 hectares. Standard Uranium plans to follow up on prospective drilling results from 2022 and test brand new high-priority targets akin to the neighboring JR Zone discovery within the new southeast claim blocks.The summer 2022 program revealed the best intersections of prospective alteration and structure to date along the Bronco and Thunderbird trends, including wide graphitic structural zones on Bronco and oxidized alteration on Thunderbird, in addition to elevated radioactivity and dravite alteration.Planned 2025 drilling will follow up on the most prospective basement structures and alteration zones intersected to date and begin testing new target areas within recently staked claim blocks.Data-driven machine learning techniques will contribute to drill targeting at Davidson River through anomaly detection and mapping of EM data, in addition to anomaly matching based on the footprints of known world-class uranium deposits in the area including the Arrow and Triple-R deposits. The machine learning techniques will also be applied to the Company's internal drilling and geochemical databases.Several kilometres of graphitic conductors remain to be tested at Davidson River, with Davidson River still containing massive blue-sky potential for high-grade discovery akin to the Arrow Deposit on the neighbouring Rook I project owned and operated by NexGen Energy Ltd.Harrison Project - Available for OptionSize & Location: Two mineral claims totalling 1,750 ha, located 22 km SSE of the Shea Creek uranium deposits and approximately 30 km SE of the past producing Cluff Lake uranium mine.Geophysical/Geological Signatures: Electromagnetic ("EM") surveys conducted in 2006-2007 outlined multiple EM zones across the project. Harrison covers approximately 6.8 km of a NW-SE conductor trends coincident with a prominent magnetic low. The trend is crosscut by several interpreted fault zones, including 4.9 km of the major Harrison fault.Prospectivity Model: The project has never been drilled and provides the Company with additional exploration exposure in the southwest Athabasca uranium district. The Company believes the newly acquired Harrison project is prospective for the discovery of high-grade* unconformity-related uranium mineralization.Stock Option and RSU GrantsThe Company also announces that, pursuant to its Omnibus Incentive Plan, it has granted stock options (the "Options") to certain directors, management, and consultants of the Company to purchase an aggregate of 367,500 common shares of the Company at the price of $0.10 per common share until October 31, 2029. Vesting of the stock options shall be as follows: 20% of the Options shall vest immediately, with a further 20% of the Options vesting every three months thereafter.In addition to the Options, the Company has also granted 1,325,000 restricted share units (the "RSUs") to certain directors and senior officers of the Company. The RSUs entitle the holder to receive one common share, the cash equivalent or a combination thereof, on the vesting date of October 31, 2025.*The Company considers uranium mineralization with concentrations greater than 1.0 wt% U3O8 to be "high-grade".** The Company considers radioactivity readings greater than 300 counts per second (cps) to be "anomalous".***Natural gamma radiation in outcrop reported in this news release was measured in counts per second (cps) using a handheld RS-125 super-spectrometer and a downhole Reflex EZ-Gamma probe. Readers are cautioned that scintillometer and gamma probe readings are not uniformly or directly related to uranium grades of the rock sample measured and should be treated only as a preliminary indication of the presence of radioactive minerals.The scientific and technical information contained in this news release has been reviewed, verified, and approved by Sean Hillacre, P.Geo., President and VP Exploration of the Company and a "qualified person" as defined in NI 43-101.Historical data disclosed in this news release relating to sampling results from previous operators are historical in nature. Neither the Company nor a qualified person has yet verified this data and therefore investors should not place undue reliance on such data. The Company's future exploration work may include verification of the data. The Company considers historical results to be relevant as an exploration guide and to assess the mineralization as well as economic potential of exploration projects.About Standard Uranium (TSXV: STND)We find the fuel to power a clean energy futureStandard Uranium is a uranium exploration company and emerging project generator poised for discovery in the world's richest uranium district. The Company holds interest in over 233,455 acres (94,476 hectares) in the world-class Athabasca Basin in Saskatchewan, Canada. Since its establishment, Standard Uranium has focused on the identification, acquisition, and exploration of Athabasca-style uranium targets with a view to discovery and future development.Standard Uranium has successfully completed three joint venture earn in partnerships on their Sun Dog, Canary, and Atlantic projects totaling over $23.8M in work commitments over the next three years from 2024-2027.Standard Uranium's Sun Dog project, in the northwest part of the Athabasca Basin, Saskatchewan, is comprised of nine mineral claims over 19,603 hectares. The Sun Dog project is highly prospective for basement and unconformity hosted uranium deposits yet remains largely untested by sufficient drilling despite its location proximal to uranium discoveries in the area.Standard Uranium's Davidson River Project, in the southwest part of the Athabasca Basin, Saskatchewan, comprises ten mineral claims over 30,737 hectares. Davidson River is highly prospective for basement-hosted uranium deposits due to its location along trend from recent high-grade uranium discoveries. However, owing to the large project size with multiple targets, it remains broadly under-tested by drilling. Recent intersections of wide, structurally deformed and strongly altered shear zones provide significant confidence in the exploration model and future success is expected.Standard Uranium's eastern Athabasca projects comprise over 42,384 hectares of prospective land holdings. The eastern basin projects are highly prospective for unconformity related and/or basement hosted uranium deposits based on historical uranium occurrences, recently identified geophysical anomalies, and location along trend from several high-grade uranium discoveries.For further information contact:Jon Bey, Chief Executive Officer, and ChairmanSuite 918, 1030 West Georgia StreetVancouver, British Columbia, V6E 2Y3Tel: 1 (306) 850-6699E-mail: info@standarduranium.caCautionary Statement Regarding Forward-Looking StatementsThis news release contains "forward-looking statements" or "forward-looking information" (collectively, "forward-looking statements") within the meaning of applicable securities legislation. All statements, other than statements of historical fact, are forward-looking statements and are based on expectations, estimates and projections as of the date of this news release. Forward-looking statements include, but are not limited to, statements regarding: the timing and content of upcoming work programs; geological interpretations; timing of the Company's exploration programs; and estimates of market conditions. Forward-looking statements are subject to a variety of known and unknown risks, uncertainties and other factors that could cause actual events or results to differ from those expressed or implied by forward-looking statements contained herein. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Certain important factors that could cause actual results, performance or achievements to differ materially from those in the forward-looking statements are highlighted in the "Risks and Uncertainties" in the Company's management discussion and analysis for the fiscal year ended April 30, 2024.Forward-looking statements are based upon a number of estimates and assumptions that, while considered reasonable by the Company at this time, are inherently subject to significant business, economic and competitive uncertainties and contingencies that may cause the Company's actual financial results, performance, or achievements to be materially different from those expressed or implied herein. Some of the material factors or assumptions used to develop forward-looking statements include, without limitation: that the transaction with the Optionee will proceed as planned; the future price of uranium; anticipated costs and the Company's ability to raise additional capital if and when necessary; volatility in the market price of the Company's securities; future sales of the Company's securities; the Company's ability to carry on exploration and development activities; the success of exploration, development and operations activities; the timing and results of drilling programs; the discovery of mineral resources on the Company's mineral properties; the costs of operating and exploration expenditures; the presence of laws and regulations that may impose restrictions on mining; employee relations; relationships with and claims by local communities and indigenous populations; availability of increasing costs associated with mining inputs and labour; the speculative nature of mineral exploration and development (including the risks of obtaining necessary licenses, permits and approvals from government authorities); uncertainties related to title to mineral properties; assessments by taxation authorities; fluctuations in general macroeconomic conditions. The forward-looking statements contained in this news release are expressly qualified by this cautionary statement. Any forward-looking statements and the assumptions made with respect thereto are made as of the date of this news release and, accordingly, are subject to change after such date. The Company disclaims any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by applicable securities laws. There can be no assurance that forward-looking statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements. Neither the TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts responsibility for the adequacy or accuracy of this release.To view the source version of this press release, please visit https://www.newsfilecorp.com/release/228449 Copyright 2024 ACN Newswire via SeaPRwire.com.
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Lima Momen Kempen Teratas di TikTok berita

Lima Momen Kempen Teratas di TikTok

(SeaPRwire) - TikTok telah muncul sebagai bahagian penting dalam landskap media kempen 2024, dengan hampir 40% orang dewasa di bawah umur 30 tahun secara tetap menggunakan platform ini untuk mendapatkan berita, menurut kajian Pew. Dengan Meta mengumumkan awal tahun ini bahawa ia tidak akan lagi mengutamakan kandungan politik, TikTok menjadi alat utama untuk menjangkau pengundi muda, walaupun kontroversi mengenai "TikTok benar-benar satu-satunya platform media sosial di mana kempen atau kumpulan politik dapat menyajikan kandungan mereka kepada orang-orang yang tidak mengikuti mereka," kata Kyle Tharp, pengarang buletin FWIW, yang menjejak politik digital. Bahawa bekas Presiden Donald Trump dan Naib Presiden Kamala Harris telah menerima media bukan tradisional seperti TikTok dan dalam kempen 2024 mereka menunjukkan peralihan di mana dan bagaimana pengundi berinteraksi dengan politik, Tharp berhujah. "Semakin meningkat, jenis pengundi yang boleh dipujuk yang [calon] perlu capai tidak menggunakan berita dan maklumat di platform arus perdana," katanya. "Mereka tidak menonton CNN, mereka tidak membaca New York Times, dan sebaliknya, ramai daripada mereka mendapatkan berita tentang pilihan raya dari platform media sosial." TIME bercakap dengan Tharp pada 31 Oktober untuk mendapatkan pandangannya tentang lima momen kempen teratas yang menjadi viral di TikTok. Dia berkata pada tahun 2024, momen paling menonjol untuk pengguna TikTok terdiri daripada penjelasan yang diteliti tentang Projek 2025 hingga lagu yang dicampur semula yang dibuat dari petikan perbahasan Trump tentang pendatang yang "memakan haiwan peliharaan." Harris menjadi calon Ketika Harris menjadi calon Demokrat pada akhir bulan Julai setelah Presiden Joe Biden menarik diri dari perlumbaan, dia menerima sokongan yang luar biasa secara dalam talian. "Ia hanya melepaskan peralihan suasana hati yang lengkap di platform tersebut," kata Tharp. Ketika Biden mengakhiri kempen pilihan raya semula dan menyokong Harris pada 21 Julai, pengikut TikTok kempen tersebut , setelah menjenamakan semula dari @BidenHQ kepada @KamalaHQ. Pengguna memeluk budaya meme, menggunting petikan Mei 2023 dari Harris, di mana dia mengingati ibunya bertanya, "Adakah anda fikir anda baru jatuh dari pokok kelapa?" dan membuat edit TikTok dalam warna hijau neon tanda tangan trend "Brat Summer" penyanyi Charli XCX. "Terdapat banyak laporan pada awal musim bunga ini di mana ia menunjukkan secara konsisten bahawa terdapat banyak sentimen negatif terhadap Joe Biden dan banyak sentimen positif terhadap Donald Trump," kata Tharp. "Dan setelah Kamala Harris menjadi calon, ia benar-benar berubah, dan kebanyakan catatan yang menyebut Harris adalah positif, dan majoriti orang yang menyebut Trump adalah negatif. Dan itu benar-benar tetap statik sepanjang kitaran pilihan raya." Perbahasan presiden Harris-Trump antara Harris dan Trump adalah satu lagi momen besar di platform tersebut. "Berjuta-juta orang menonton perbahasan di televisyen tradisional, tetapi puluhan juta orang menonton perbahasan di TikTok," kata Tharp. "Mungkin mereka tidak benar-benar peduli untuk duduk dan menonton segmen TV selama 90 minit, tetapi mereka akan menatal melalui suapan mereka untuk melihat klip teratas atau apa yang orang katakan tentang perbahasan itu." Dakwaan palsu Trump tentang menjadi audio yang sedang tren, sementara video tindak balas Harris terhadap beberapa komen Trump "menjulang seperti api" di platform tersebut, kata Tharp. Projek 2025 Kandungan yang menerangkan , inisiatif dari Yayasan Warisan konservatif yang mengemukakan cadangan dasar untuk Presiden Republikan seterusnya, membuat gelombang di TikTok awal tahun ini. Kandungan tersebut terutamanya mengambil bentuk penjelasan, memecahkan kesan dasar yang dicadangkan. (Trump telah menjauhkan diri dari Projek 2025.) "Dari April hingga Jun, kita benar-benar melihat banyak pencipta individu, bukan hanya kempen, tetapi pencipta individu yang bercakap tentang Projek 2025, di TikTok," kata Tharp. Stunt McDonald's Trump Klip video Trump menghidangkan kentang goreng di McDonald's di Pennsylvania pada 20 Oktober telah menjana angka yang besar di platform tersebut. "Stunt Trump di McDonald's… benar-benar membuahkan hasil untuk kempennya di TikTok. Ia menjana lebih daripada 200 juta tontonan pada kepingan kandungan tentangnya, yang sangat liar dan tidak dijangka," kata Tharp. "Ramai rakyat Amerika menganggap Trump sebagai bintang realiti TV yang melakukan perkara-perkara yang aneh seperti kartun," tambah Tharp, "dan jenis tingkah laku itu benar-benar memikat penonton." Pengesahan selebriti dan pencipta sepanjang 100 hari yang lalu telah menarik banyak penglibatan, kata Tharp. Kempen Harris telah menemui kejayaan dengan menyiarkan video yang menampilkan Barack dan , dan selebriti seperti Usher, sementara kempen Trump telah melihat kejayaan memanfaatkan influencer seperti Jake dan Logan Paul dan jutawan . "Kebanyakan orang pergi ke TikTok untuk kandungan bukan politik, dan oleh itu apabila anda dapat menunjukkan selebriti dan orang bukan politik dalam kandungan anda, ia mungkin lebih menonjol," kata Tharp.Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Mazda Launches Redesigned Corporate Website JCN Newswire

Mazda Launches Redesigned Corporate Website

HIROSHIMA, Japan, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Mazda Motor Corporation today launched a redesigned corporate website. Amid growing awareness and interest in sustainability, the company redesigned its website to provide stakeholders visiting the corporate website with more timely and user-friendly access to financial and non-financial data as well as information about initiatives set to enhance both corporate and social value.Within the corporate website, it also set up MAZDA MIRAI BASE, a new owned-media platform filled with videos and photos, to share stories about Mazda’s work to build a better future.Mazda Motor Corporation Website URL:Japanese - www.mazda.com/ja/English - www.mazda.com/en/MAZDA MIRAI BASE URL:Japanese - www.mazda.com/ja/mazda-mirai-base/English - www.mazda.com/en/mazda-mirai-base/Key ImprovementsMazda’s website that presents the company’s worldview more clearly offering enhanced usabilityTo help our stakeholders quickly find information they need and access a broader range of corporate data, Mazda redesigned its website structure and reorganized the information posted. In addition, the content was optimized to convey Mazda’s corporate philosophy, established last year, and value creation approach, arranging these in a restructured corporate website that articulates our worldview seeking to create a vibrant future.New MAZDA MIRAI BASE platformThis new owned-media platform MAZDA MIRAI BASE has been created to share Mazda’s aspirations and initiatives for realizing its corporate philosophy and 2030 Vision. Working from the concept of a “media platform that connects with partners to create an exciting future,” MAZDA MIRAI BASE distributes articles, video and photos to tell stories about ”creating the joy of living” found in manufacturing safe and reliable automobiles, manufacturing sustainably, and creating moving experiences.Mazda will continue to pursue the ‘Joy of Driving’ under its core value “Human Centric,” and aim to deliver the ‘Joy of Living’ by creating moving experiences in customers' daily lives.Reference:Mazda’s Corporate Philosophy- Japanese https://www.mazda.com/ja/about/philosophy/- English https://www.mazda.com/en/about/philosophy/ Copyright 2024 JCN Newswire via SeaPRwire.com.
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NTT and Toyota Motor Corporation agree to joint initiative in the field of mobility and AI/telecommunications with the aim of realizing a society with zero traffic accidents JCN Newswire

NTT and Toyota Motor Corporation agree to joint initiative in the field of mobility and AI/telecommunications with the aim of realizing a society with zero traffic accidents

Toyota City, Japan, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Today, Toyota Motor Corporation (hereafter, Toyota) and Nippon Telegraph and Telephone Corporation (hereafter, NTT) have agreed to a joint initiative in the field of mobility and AI/telecommunications with the aim of realizing a society with zero traffic accidents.Through their previous collaborations, the two companies have confirmed that they share common values, such as contributing to society through technological and industrial development, a people-centered approach, and global contributions that start in Japan. This time, they will further deepen their collaboration with the aim of achieving a "society with zero traffic accidents" as the first step towards realizing a prosperous mobility society where safety and freedom are in harmony.In order to achieve a society with zero traffic accidents, it is necessary to take an infrastructure-cooperative approach that constantly connects people, mobility and infrastructure, in addition to the advancement of driving support technology based on data-driven technology in cars and the development of future automated driving technology.To achieve both of these things, Toyota is developing Software Defined Vehicles (SDV) with safety and security as the top priority. Alongside the evolution of SDV, it will become more important to build infrastructure such as a high-speed, high-quality communication infrastructure, an AI infrastructure that can collect and intelligently process vast amounts of information, and a computing infrastructure.In this collaboration, NTT, whose strengths lie in the telecommunications, and Toyota will jointly build a "Mobility AI Platform" that combines a seamless communications infrastructure with AI and computing platforms that can intelligently process large amounts of data. By doing so, they aim to connect people, mobility, and infrastructure to realize a safe, secure, and sustainable mobility society with no traffic accidents.Details of the joint initiativeWe will jointly develop and operate the "Mobility AI Platform" and use it in our efforts(1) to achieve a society with zero traffic accidents. The Mobility AI Platform is made up of multiple elements(2).The Mobility AI Platform aims to standardize the mobility field, and we envision that it will be used not only by the two companies, but also by a wide range of industry, government, and academic partners who share the goal of realizing a society with zero traffic accidents.Through this initiative, the two companies expect to invest a total of 500 billion yen by 2030. Starting in 2025, they will begin development of the Mobility AI Platform, and from around 2028 under the three-pronged infrastructure, they will begin social implementation and collaboration with various partners, aiming for widespread adoption from 2030 onwards.(1) Main initiatives aimed at achieving a society with zero traffic accidents- Three-pronged infrastructure collaboration" to prevent collisions at blind intersections, etc.- Development of advanced driving support/future automated driving systems" that are data-driven, with AI learning on its own based on large amounts of driving data(2) Elements that make up the mobility AI platform1. Distributed computing platform (data center)Computing resources (data centers) for analyzing and processing vast amounts of data using AI are installed in distributed locations, utilizing IOWN's optical communication technology. By locating them in areas rich in renewable energy, we can achieve local production for local consumption of electricity, and by achieving high power efficiency in the coordination and processing of distributed computing resources and AI, we can promote the greening of the vast amounts of electricity needed for data analysis and processing.2. Intelligent communication infrastructureA system is being built to coordinate human mobility infrastructure through seamless communication that is suitable for various traffic environments and conditions in urban areas, rural areas, and suburbs. In addition to being highly reliable, it also achieves low-latency communication for large volumes of data.3. AI infrastructureA platform that achieves mobility AI that learns and infers from various data from human mobility infrastructure, based on a "distributed computing infrastructure (data center)" and "intelligent communication infrastructure". Copyright 2024 JCN Newswire via SeaPRwire.com.
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Trump Bangkitkan Dakwaan Penipuan Tidak Berasaskan di Pennsylvania yang Penting berita

Trump Bangkitkan Dakwaan Penipuan Tidak Berasaskan di Pennsylvania yang Penting

(SeaPRwire) - Selama berbulan-bulan, Donald Trump telah menunjukkan keyakinan di medan kempen bahawa dia bersedia untuk mengalahkan Naib Presiden Kamala Harris. Tetapi dengan kurang daripada seminggu sebelum Hari Pilihan Raya, dia sedang menanam benih untuk mengatakan bahawa pilihan raya itu dicuri jika dia kalah. Bekas Presiden itu telah meningkatkan retorikanya minggu ini untuk menimbulkan keraguan terhadap integriti hasil, terutamanya di medan pertempuran penting Pennsylvania, di mana Trump dan Harris dalam tinjauan pendapat. Beliau mengadakan sidang akhbar pada hari Selasa di Mar-a-Lago, dengan mengatakan bahawa terdapat "beberapa tempat yang buruk di Pennsylvania di mana beberapa perkara serius telah ditangkap atau sedang dalam proses ditangkap." Di media sosial, beliau mendakwa bahawa Daerah York telah menerima "RIBUAN Borang Pendaftaran Pengundi dan Permohonan Undi Melalui Surat yang mungkin PENIPUAN daripada kumpulan pihak ketiga." Daerah Lancaster, katanya, telah "tertangkap dengan 2600 Undi dan Borang Palsu." Pada hari Rabu, kempennya menyaman Daerah Bucks, di luar Philadelphia, kerana didakwa menolak pengundi Trump daripada menghantar permohonan undian melalui surat. "Pennsylvania menipu, dan tertangkap, dalam skala besar yang jarang dilihat sebelum ini," katanya di Truth Social. Itu bukan gambaran yang tepat tentang fakta. Pegawai Daerah York mengesahkan penghantaran bahan berkaitan pilihan raya yang mencurigakan, termasuk borang pendaftaran pengundi dan permohonan undian melalui surat, ke pejabat daerah, tetapi mengasingkannya untuk diperiksa. Penguatkuasaan undang-undang dan pegawai pilihan raya Daerah Lancaster juga mengesahkan "kejadian penipuan pendaftaran pengundi yang disyaki" yang mungkin berpunca daripada "operasi penceritaan berskala besar," kata mereka, melancarkan siasatan. Masih belum diketahui organisasi mana yang mengemukakan bahan pilihan raya—atau calon mana yang mereka sokong. Apa pun, pakar pilihan raya berkata, insiden tersebut membuktikan sebaliknya daripada pegawai Pennsylvania yang menipu. Sebaliknya, ia menunjukkan bahawa mereka berjaya mencegah kecurangan pilihan raya. "Sistem ini berfungsi dalam kes ini," kata Tammy Patrick, yang mengarahkan Persatuan Pegawai Pilihan Raya Kebangsaan, "kerana permohonan pendaftaran yang dikemukakan yang meragukan telah diasingkan dan sedang disiasat." Pegawai Daerah Bucks juga menolak dakwaan GOP, yang tersebar luas di media sosial, bahawa penyokong Trump dicegah daripada memohon undian melalui surat pada hari Selasa di daerah antara pendaftar Demokrat dan Republikan. Tetapi ia mengakui "kesalahpahaman" lebih awal pada hari itu. Ramai pengundi, kata mereka, fikir mereka beratur untuk mengundi secara peribadi, bukan untuk memohon undian melalui surat, yang boleh mereka isi dan hantar di tempat atau dikembalikan sebelum Hari Pilihan Raya. Video menunjukkan bahawa pegawai di satu lokasi cuba membahagikan barisan yang panjang dan memberitahu orang ramai bahawa mereka tidak akan dapat mengundi, menimbulkan kekeliruan di kalangan sesetengah pengundi. Klip kejadian itu oleh influencer sayap kanan termasuk jutawan Elon Musk, yang mempunyai lebih daripada 200 juta pengikut di X, yang dahulunya dikenali sebagai Twitter, mencetuskan kemarahan dalam talian yang meluas. Pada hari Rabu, mahkamah Pennsylvania berpihak kepada saman kempen Trump, yang melanjutkan tarikh akhir untuk memohon undian melalui surat di Daerah Bucks sehingga hari Jumaat. Jurucakap kempen Harris, Ian Sams mengejek dakwaan penipuan Trump pada hari Rabu, tangkapan skrin di X salah satu hantaran media sosialnya. "Ini bukan apa yang seseorang siarkan jika mereka benar-benar yakin tentang kedudukan mereka di Pennsylvania," tulis Sams. Pertempuran itu adalah tanda perlumbaan berisiko tinggi di Pennsylvania, yang akhirnya boleh menentukan pilihan raya, dan sejauh mana Trump dan sekutunya sedang meletakkan asas untuk mencabar hasil di sana jika dia gagal. Bekas Presiden itu memegang kelebihan kurang daripada setengah peratusan mata dalam tinjauan pendapat negeri terkini 538 , dan ramai penganalisis berkata beliau perlu memenangi Keystone State untuk memenangi Kolej Pilihan Raya. Pada tahun 2020, Presiden Joe Biden memenangi Pennsylvania dengan kurang daripada satu peratusan mata. Kini, rangkaian organisasi pro-Trump sedang menumpukan jutaan ringgit kepada negara itu untuk meningkatkan kehadiran GOP. Dalam peringkat akhir pilihan raya, Musk telah mendermakan lebih daripada $118 juta kepada jawatankuasa tindakan politiknya, America PAC, untuk menggalakkan penyokong Trump yang kurang cenderung hingga sederhana untuk mengundi awal di negeri ayun yang kritikal ini. Usaha ini menandakan perbezaan bagi Republikan daripada empat tahun lalu, ketika Trump meminta pengikutnya untuk mengundi pada Hari Pilihan Raya dan mengelakkan undian melalui surat, sistem yang dia cerca sebagai penuh dengan penipuan. Kali ini, pegawai kempen utama Trump telah meyakinkannya bahawa ia merugikan diri sendiri untuk mengkritik undian awal, kerana ia membolehkan pihak lawan memperoleh kelebihan kompetitif sambil menghalang penyokongnya daripada mengundi langsung. Walaupun kem Trump, bersama-sama dengan kumpulan sekutu, telah membina infrastruktur untuk mengelakkan mengulangi kesilapan yang sama, pengkritik mengatakan aduannya yang mendahului tentang "penipuan" mengikuti playbook yang biasa. "Ini hanyalah ulangan tahun 2016, ketika dia mengatakan bahawa kemenangan Ted Cruz dalam kaukus Iowa adalah disebabkan oleh penipuan, dan tahun 2020 ketika dia mengatakan bahawa kemenangan Joe Biden dalam perlumbaan presiden adalah disebabkan oleh penipuan," kata Whit Ayres, seorang ahli strategi Republikan veteran. "Ia sudah menjadi kebiasaan." Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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All-New Triton Wins Golden Award at VMARK Vietnam Design Awards 2024 JCN Newswire

All-New Triton Wins Golden Award at VMARK Vietnam Design Awards 2024

TOKYO, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Motors Corporation (hereafter, Mitsubishi Motors) announced that the all-new Triton has been selected as a golden award winner at the VMARK Vietnam Design Awards 2024 in the Best Transportation Design category. This marks the second time that Mitsubishi Motors has won the award, after the Xforce topped the same category in 2023.Established in 2018, the VMARK Vietnam Design Awards is organized by the VDAS Design Association based in Ho Chi Minh City. This year, a jury of 42 internationally renowned design practitioners evaluated design projects from Vietnam and around the world, and each entry was evaluated against the five criteria of innovativeness, eco-friendliness, identity, functionality, and community. The most outstanding designs received the golden award, and this year, 19 projects were selected as gold award winners out of a total of 700 entries.The Triton is Mitsubishi Motors' one-ton pickup truck that traces its roots back to the Forte originally released in 1978. In the 45 years since, this global strategic vehicle from Mitsubishi Motors has sold a cumulative total of approximately 5.7 million units in approximately 150 countries spanning five generations of models. Developed under the product concept of "Power for Adventure," the all-new Triton features a complete overhaul of everything from the interior and exterior design to the chassis, ladder frame and engine, and more. It was first launched in Thailand – where its production site is located – in July 2023 and introduced in Japan in February 2024. The all-new Triton is being rolled out sequentially in 100 countries worldwide.In attending the VMARK Vietnam Design Award 2024 ceremony, Kazuhiro Watanabe, Division General Manager of Sales & Marketing Division, Mitsubishi Motors Vietnam Co., Ltd., commented: “This award is a testament to our 30-year journey of 'Drive ahead together for everyday Adventure' in Vietnam. The all-new Triton embodies this commitment by delivering exceptional quality, innovation, and a driving experience that resonates with the adventurous spirit of the Vietnamese people.”Norihiko Yoshimine, Product Design Director, Mitsubishi Motors, who designed the Triton, cheerfully commented, “The Triton expresses the majestic aura that is distinctively Mitsubishi, possessing both robustness and agility in addition to the toughness and sheer power expected of a pickup truck. Following in the footsteps of the award for the Xforce last year, I am deeply honored that the all-new Triton has earned such high recognition at the VMARK Vietnam Design Awards this year. This award will provide a boost, but we will also continue doing our utmost to promote the Triton’s appeal to even more customers in Vietnam.”VMARK Vietnam Design Awards 2024 Awards Page (only available in English and Vietnamese) https://www.vietnamdesignweek.org/vmark-vietnam-design-week-2024About Mitsubishi MotorsMitsubishi Motors Corporation (TSE:7211) — a member of the Alliance with Renault and Nissan — is a global automobile company based in Tokyo, Japan, which has about 28,000 employees and a global footprint with production facilities in Japan and the ASEAN region. Mitsubishi Motors has a competitive edge in SUVs, pickup trucks and plug-in hybrid electric vehicles, and appeals to ambitious drivers willing to challenge convention and embrace innovation. Since the production of our first vehicle more than a century ago, Mitsubishi Motors has been a leader in electrification — launched the i-MiEV, the world’s first mass-produced electric vehicle in 2009, followed by the Outlander PHEV, the world’s first plug-in hybrid electric SUV in 2013. With a target of increasing the sales ratio of electrified vehicles to 100% by 2035, Mitsubishi Motors will deliver models that embody Mitsubishi Motors-ness and contribute to the realization of a carbon-neutral society.For more information on Mitsubishi Motors, please visit the company's website athttps://www.mitsubishi-motors.com/en/ Copyright 2024 JCN Newswire via SeaPRwire.com.
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Eisai Presents Data on Benefits of Long-Term Administration of Dual-Acting Lecanemab at the 17th Clinical Trials for Alzheimer’s Disease (CTAD) Conference JCN Newswire

Eisai Presents Data on Benefits of Long-Term Administration of Dual-Acting Lecanemab at the 17th Clinical Trials for Alzheimer’s Disease (CTAD) Conference

TOKYO and CAMBRIDGE, Mass., Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Biogen Inc. announced today that the latest findings for lecanemab-irmb (U.S. brand name: LEQEMBI®), an anti-amyloid beta (Aβ) protofibril* antibody for the treatment of early Alzheimer’s disease (AD), were presented at the Clinical Trials for Alzheimer's Disease Conference (CTAD), held in Madrid, Spain, and virtually.Benefits of Continued Treatment with Lecanemab for People with Early ADIn July 2024 at the Alzheimer's Association International Conference (AAIC) 2024, results from the open-label long-term extension study (OLE) following the core study of the lecanemab Phase 3 Clarity AD study were presented, showing that the mean change from baseline in CDR-SB (global cognitive and functional scale) in the lecanemab treated group relative to the placebo group was -0.45 at 18 months, and at 36 months, this expanded to -0.95 compared to a prespecified natural history** cohort of AD. There was a 30% reduction in the relative risk of progressing to the next disease stage In addition, the tau PET substudy of the lecanemab Phase 3 Clarity AD clinical study showed that with three (3) years of continuous treatment with lecanemab, 59% of patients with no or low tau accumulation in the brain (no tau/low tau) at baseline showed improvement or no decline, and 51% showed improvement from baseline on the Clinical Dementia Rating-Sum of Boxes (CDR-SB) global cognitive and functional scale.1Clarity AD data presented at CTAD expand on these initial results to include additional measurements resulting from three (3) years of continuous lecanemab treatment in patients with low levels of amyloid accumulation in the brain at baseline (less than 60 Centiloids: low amyloid). These data show that 46% of patients improved or had no decline, and 33% showed improvement from baseline on the CDR-SB. On the ADAS-Cog14 measurement scale, 46% of patients showed improvement or no decline and 43% showed improvement. On the ADCS MCI-ADL, 51% of patients showed improvement or no decline and 48% showed improvement. These results – from no tau/low tau population and low amyloid populations – suggest that earlier initiation of lecanemab treatment may have a positive impact on disease progression of early AD patients and may provide continued benefits to patients with early AD over the long term.2No new safety findings were observed with continued lecanemab treatment over three (3) years. Most amyloid-related imaging abnormalities (ARIA) occurred in the first six (6) months of treatment. After the first six (6) months, ARIA rates were low and similar to ARIA rates on placebo during the placebo- controlled period. With regards to the incidence of ARIA by ApoEε4 status during the continuous treatment, the incidence was higher in ApoE4 homozygotes than in heterozygotes or non-carriers, but rates of new ARIA were decreased after the completion of the 18 months core study as treatment continued, regardless of ApoEε4 status.2Correlation between Protofibrils and Biomarkers for Neurodegenerative Disease in the AD Brain Dual-acting lecanemab is the only early AD treatment available to support neuronal function by clearing the highly toxic protofibrils that continue to cause neuronal injury and death even after plaques have been cleared from the brain. Protofibrils accumulate early in the AD brain and lead to nerve cell function loss, abnormal nerve processes, inflammation, and memory loss. In non-clinical studies, antibodies against protofibrils prevented protofibril-mediated neuronal dysfunction and memory loss.Accurately quantifying the amount of protofibrils in human cerebrospinal fluid (CSF) has been challenging due to their low concentration. As such, a new measurement method was developed by researchers at Eisai to accurately quantify protofibrils in CSF.Utilizing this new method of measurement, the amount of protofibrils in AD CSF correlated more strongly with neurodegenerative disease biomarkers (CSF total tau and neurogranin) than with CSF Aβ42, a biomarker associated with Aβ plaques accumulation, indicating that protofibrils are closely related to synaptic dysfunction. Furthermore, it was observed that protofibrils, unlike plaques, are diffusible. These results suggest that protofibrils induce synaptic dysfunction, playing an important role in neurodegeneration in AD brains.3Lecanemab Treatment for Early AD: Insights from Long-Term U.S. Clinical StudiesDr. Marwan Noel Sabbagh, Moreno Family Chair for Alzheimer's Research and Vice Chairman for Research and Professor, Department of Neurology, Barrow Neurological Institute, presented outcomes of an analysis of the use of lecanemab treatment between January 6, 2023, and July 30, 2024, based on payment claims data from the Komodo Research Database, a medical database in the U.S. In the U.S., lecanemab is used in accordance with the US FDA-approved indication, dosing, and monitoring guidelines. The analysis found that access to lecanemab treatment is expanding and highlighted opportunities to improve access in rural areas and educational outreach for underserved populations.4Dr. David Watson of the Alzheimer's Research and Treatment Center reported on patients who continued to receive lecanemab treatment following the Phase II Study 201 and Phase III Clarity AD study. A total of 136 patients participated in both studies at this center, and 66 patients chose to continue lecanemab therapy, with 13 patients receiving treatment for more than five (5) years and 40 patients receiving treatment for more than three (3) years. More than half of the patients (15/24) who continued treatment with lecanemab for more than three (3) years after the core phase remained in their initial stage of disease. Further, in a survey of 11 patients (or their caregivers) who received lecanemab treatment for more than five (5) years, all patients responded that they were “very satisfied” or “satisfied” with lecanemab treatment. In addition, between 45% and 73% of patients responded that lecanemab treatment made them feel more positive about their daily life, social activities, memory, etc. "frequently" or "very often."5No new long-term safety findings were observed in these multi-year studies.5Progress in the AHEAD 3-45 Study: Improving Screening Eligibility Using Blood Biomarkers and Completing Patient EnrollmentAHEAD 3-45 is a Phase 3 clinical study for individuals with preclinical AD, meaning they are clinically unimpaired but have intermediate or elevated levels of amyloid in their brains. In the study, blood tests, cognitive function tests (PACC-5***), amyloid PET, MRI, and tau PET were used for screening. Based on the amount of Aβ accumulation in the brain as determined by amyloid PET, subjects were assigned to two (2) trials with different dose settings: the A3 trial, for those with borderline Aβ levels in the brain, and the A45 trial, for those with positive Aβ levels in the brain.6Screening with blood biomarker tests was important to improve eligibility for amyloid PET testing in subjects without cognitive impairment. Using plasma Aβ42/40 ratio and p-tau217/tau217 ratio in theinitial screening reduced screening failure on amyloid PET from more than 70% to less than 30%. In particular, plasma p-tau217 was shown to correlate with amyloid PET, supporting its role as a useful blood biomarker to identify elevated amyloid in the brain.6Enrollment for the AHEAD 3-45 study was completed in October 2024.Lifetime Achievement Award Presented to Professor LannfeltProfessor Emeritus Lars Lannfelt of Uppsala University received the CTAD Lifetime Achievement Award in recognition of his pioneering work in scientific discovery and drug development in AD. As part of this award ceremony, he delivered a keynote speech outlining the discovery of the arctic mutation in familial AD, its application to therapeutic strategies targeting protofibrils for AD treatment, and the development of lecanemab.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with both Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision- making authority.*Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline of this progressive, debilitating condition.7 Protofibrils cause injury to neurons in the brain which, in turn, can negatively impact cognitive function through multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.8**ADNI is a clinical research project launched in 2005 to develop methods to predict the onset of AD and to confirm the effectiveness of treatments. The ADNI observational cohort was pre-specified and used during the design of Clarity AD. The cohort represents the exact population of those in Clarity AD study; matched ADNI participants show similar degree of decline to placebo group out to 18 months.***PACC-5 is a composite measure that provides a highly sensitive measure of changes in cognitive function in individuals with preclinical AD.About lecanemab (LEQEMBI®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab is approved in the U.S., Japan, China, South Korea, Hong Kong, Israel, the United Arab Emirates and Great Britain. Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union (EU).LEQEMBI’s approvals in these countries were based on Phase 3 data from Eisai’s, global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results. The primary endpoint was the global cognitive and functional scale, Clinical Dementia Rating Sum of Boxes (CDR-SB). In the Clarity AD clinical trial, treatment with lecanemab reduced clinical decline on CDR-SB by 27% at 18 months compared to placebo.9,10 The mean CDR- SB score at baseline was approximately 3.2 in both groups. The adjusted least-squares mean change from baseline at 18 months was 1.21 with lecanemab and 1.66 with placebo (difference, −0.45; 95% confidence interval [CI], −0.67 to −0.23; P
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Eisai Presents Latest Clinical Findings Suggesting Inhibition of Tau Propagation by Anti-MTBR Tau Antibody E2814 at the 17th Clinical Trials on Alzheimer’s Disease Conference (CTAD) JCN Newswire

Eisai Presents Latest Clinical Findings Suggesting Inhibition of Tau Propagation by Anti-MTBR Tau Antibody E2814 at the 17th Clinical Trials on Alzheimer’s Disease Conference (CTAD)

TOKYO, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co. Ltd announced today that the latest findings on anti-MTBR (microtubule binding region) tau antibody E2814 were presented at the 17th annual Clinical Trials on Alzheimer’s Disease (CTAD) conference, held in Madrid, Spain, and virtually. Eisai also announced initiation of a Phase II study (Study 202) on E2814 for sporadic early Alzheimer’s Disease (AD).Impact of the anti-MTBR tau antibody E2814 on tau pathology biomarkers in Dominantly Inherited Alzheimer’s Disease (DIAD)E2814 is an investigational anti-MTBR tau antibody designed to target the MTBR of tau. In AD patients, neurofibrillary tangles (NFT) are a pathological hallmark, and they are believed to spread through synaptically connected pathways in the brain, forming the tau propagation hypothesis. It is thought that tau propagation is drivenby the specific tau species containing MTBR, tau seeds that spread tau pathology to different brain regions important for cognition and function.Eisai conducted a Phase I/II clinical study (Study 103, NCT04971733; 7 participants) of the anti-MTBR tau antibody E2814 in patients with Dominantly Inherited Alzheimer’s Disease (DIAD) beginning in June 2021. This study aimed to evaluate the safety and tolerability of E2814 in DIAD patients, with a primary objective of assessing the target engagement of E2814 with MTBR-tau species in their cerebrospinal fluid (CSF). In addition, pharmacodynamicevaluation was performed using multiple biomarkers related to AD tau pathology. In the study, DIAD patients withclinical symptoms were administered E2814 for 12 to 24 months. Data from the Dominantly Inherited Alzheimer Network Observational Study (DIAN-obs), an observational cohort of DIAD, were used as references to evaluate biomarkers changes in E2814 treatment.Compared to the reference data from DIAN-obs, patients who received E2814 showed approximately 75% and 50% reductions of CSF MTBR-tau243 and p-tau217, respectively, reflecting tau pathophysiology. Additionally, braintau accumulation observed by tau PET was stabilized or trended toward decrease in DIAD subjects administered E2814. These results suggest that E2814 inhibited tau propagation and suppressed the accumulation of tau aggregates in brains of people living with DIAD. This will be further investigated in the ongoing Phase II/III Tau NexGen study (NCT05269394) with DIAD patients and the Phase II 202 study (NCT06602258) with sporadic early Alzheimer’s disease (AD) patients.Initiation of Phase II clinical study (Study 202)In September 2024, Eisai initiated a Phase II clinical study (Study 202) for individuals with early AD in the United States. The study is also scheduled to be conducted in Japan in the future. This study is a placebo- controlled,double-blind, parallel-group, dose exploration study, evaluating the safety, tolerability, and biomarker efficacy of E2814 in people living with early AD receiving lecanemab as a backbone anti-Aβ therapy.Eisai positions neurology as a key therapeutic area, and it will continue to create innovation in the development of novel medicines based on cutting-edge neurology research as it seeks to contribute further to improving the benefits of affected individuals and their families in diseases with high unmet needs, such as dementia including AD.This release discusses investigational uses of agents in development and is not intended to convey conclusionsabout efficacy or safety. There is no guarantee that such investigational agents will successfully complete clinical development or gain health authority approval.About E2814An investigational anti-microtubule binding region (MTBR) tau antibody, E2814 is being developed as a disease- modifying agent for tauopathies including sporadic Alzheimer’s disease (AD). Phase I clinical studies are underway. E2814 was discovered as part of the research collaboration between Eisai and University College London. E2814 is designed to prevent the spreading of tau seeds within the brains of affected individuals. In addition, E2814 has been selected as an anti-tautherapy in a Phase II/III Tau NexGen study for the treatment of DIAD, conducted by DIAN-TU led by Washington University School of Medicine in St. Louis, is underway.Biomarkers related to AD tau pathologyAs fluid biomarkers related to AD tau pathology, tau containing the residue 243 (MTBR-tau243) and tau phosphorylated at theresidue 217 (p-tau217) in CSF have been reported.1 In addition, positron emission tomography (tau PET), which specifically detects tau aggregates, is used as an imaging biomarker. These biomarkers are included in the Revised criteria for diagnosis and staging of Alzheimer's disease published by the National Institute on Aging and the Alzheimer's Association (NIA-AA) in June 2024.2(1) Horie K, et al. CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease. Nat Med. 2023. 29. 1954-1963(2) Jack Jr. CR, et al. Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup. Alzheimers Dement. 2024. 20. 5143-5169For further information: Media Inquiries:Eisai Co., Ltd.Public Relations Department TEL: +81 (0)3-3817-5120Eisai Inc. (U.S.) Libby Holman+1-201-753-1945Libby_Holman@Eisai.comEisai Europe, Ltd. (UK, Europe, Australia, New Zealand and Russia) EMEA Communications Department+44 (0) 786 601 1272EMEA-comms@eisai.net Copyright 2024 JCN Newswire via SeaPRwire.com.
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Beginner’s Guide to Travel Credit Cards ACN Newswire

Beginner’s Guide to Travel Credit Cards

SINGAPORE, Oct 31, 2024 - (ACN Newswire via SeaPRwire.com) - Whether you're a frequent business traveller who's always on the go or a world explorer looking for your next adventure, a travel credit card can be a great way to make the best of your trips. The right travel credit card can enhance your travel experiences by offering opportunities to earn rewards, redeem rewards on travel expenses, access discounts and deals, and get perks and benefits like lounge access and travel insurance. Learn all about travel credit cards, what they can do for you and how to choose the right one in our guide below.What is a travel credit card?You may have heard of credit cards that offer discounts and savings on fuel, groceries or shopping. A travel credit card is a type of credit card that offers perks and rewards that make travel smooth and convenient. While the exact reward programs differ from one card to the next, what most miles credit cards have in common is that they grant users benefits and redemption opportunities specifically linked to travel.A travel credit card is a great way to turn everyday spending into travel rewards. Generally, a miles credit card or travel card will let you earn points, miles, or cashback on purchases, which you can redeem for travel-related expenses like flight tickets, hotel stays, car rentals, and more. Over time, savvy cardmembers may accumulate enough rewards to cover the full cost of a small vacation. Many travel credit cards also include benefits like complimentary lounge access, travel insurance, and exclusive discounts with partner airlines and hotels.Pros and Cons of a Travel Credit CardProsEarning points and miles: Your miles credit card helps you earn rewards on eligible purchases. If you use your credit card regularly for eligible purchases, your points or miles can add up quickly and bring you significant savings on your next trip.Sign-up bonuses: In addition to regular rewards, your card may offer a welcome bonus that lets you earn a significant number of points/miles if you meet certain spending criteria. These bonuses can provide a great boost to your rewards balance right from the start.Access to Airport Lounges: Your travel credit card may also include complimentary access to airport lounges, allowing you to enjoy a more relaxed travel experience with amenities like refreshments and comfortable seating before your flight.ConsHigh annual fees: Travel credit cards with good benefits may carry higher annual fees than regular cards. You'll need to review the costs and benefits associated with your credit card to decide if the travel benefits are worth the annual fee.Complex rewards systems: Rewards programs are only useful if you know how to use them well. It might take some time and effort to fully understand how to maximize your rewards.How to Choose a Travel Credit CardWhen choosing a travel or miles credit card in Singapore, consider your travel habits and preferences. Start by considering how often you travel. A card with a high fee may be worth it for frequent fliers, but if you only take one or two trips a year, seek out a card with a low or no annual fee with points that don't expire. You'll need to consider what benefits matter to you. Do you value lounge access, or is travel insurance more important? Choose a card that offers benefits that match your needs. Lastly, look for a rewards program that fits in with your lifestyle. If you spend a lot on dining and shopping, look for a card that offers higher rewards in those categories. Additionally, carefully review the points/redemption process before you apply for a travel credit card. A complex redemption process can be off-putting especially if there are many limits placed on redemption.Notice:Opinions, analyses, reviews, or recommendations expressed in this article are those of the select editorial staff's alone, and have not been reviewed, approved, or otherwise endorsed by any third party.Contact Information:Name: Sonakshi MurzeEmail: Sonakshi.murze@iquanti.comJob Title: ManagerSOURCE: iQuanti Copyright 2024 ACN Newswire via SeaPRwire.com.
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1.93% lebih awal daripada jadual! Tembok latihan di Delta Batang Baram untuk Pelabuhan Miri telah mencapai 310 meter SeaPRwire

1.93% lebih awal daripada jadual! Tembok latihan di Delta Batang Baram untuk Pelabuhan Miri telah mencapai 310 meter

Sejak permulaan pembinaan, projek tembok latihan dan pengorekan pelabuhan Miri di Delta Batang Baram di Miri, Sarawak-yang dilaksanakan oleh usaha sama Rimbun Prima Sdn Bhd dan China Communications Construction Company (M) Sdn Bhd-telah berkembang dengan stabil mengikut jadual yang ditetapkan. Pasukan projek telah bekerja dengan rapat dan mencapai kemajuan yang ketara. Pada masa ini, kemajuan keseluruhan yang dirancang adalah 1.57% lengkap dan penyelesaian sebenar adalah 3.50%, 1.93% lebih awal daripada jadual. Pelan tahunan untuk tembok latihan adalah untuk menyiapkan 300 meter, dan kemajuan fizikal sebenar telah mencapai 310 meter. Dengan bermulanya musim monsun, jabatan projek akan secara aktif melaksanakan siri kerja persiapan untuk memastikan pembinaan berskala penuh yang lancar pada tahun depan. Sepanjang tempoh monsun, fokus akan diberikan kepada pembaikan, penyelenggaraan, dan pengubahsuaian peralatan marin seperti kapal peletakan geotekstil, tongkang penentuan, tongkang batu, dan jengkaut untuk memberikan sokongan peralatan yang mencukupi. Selain itu, projek ini merancang untuk mempercepatkan penimbunan bahan batu untuk memastikan bekalan yang tidak terputus sepanjang tempoh pembinaan tahun depan. Terletak di muara Batang Baram, projek ini terutamanya merangkumi dua tembok latihan berperingkat 6 kilometer dan pengorekan saluran muara sepanjang 6 kilometer. Setelah selesai, ia akan memberikan sokongan yang kuat untuk pembangunan seterusnya Pelabuhan Dalam Laut Miri dan membawa manfaat ekonomi kepada pelbagai sektor di Sarawak.
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