TOKYO and CAMBRIDGE, Mass., Jan 28, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Biogen Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved the Supplemental Biologics License Application (sBLA) for once every four weeks lecanemab-irmb (U.S. brand name: LEQEMBI®) intravenous (IV) maintenance dosing. LEQEMBI is indicated for the treatment of Alzheimer's disease (AD) in patients with mild cognitive impairment (MCI) or mild dementia stage of disease (collectively referred to as early AD) in the U.S. After 18 months of once every two weeks initiation phase, a transition to the maintenance dosing regimen of 10 mg/kg once every four weeks may be considered or the regimen of 10 mg/kg once every two weeks may be continued.The sBLA is based on modeling of observed data from the Phase 2 study (Study 201) and its long-term extension (LTE) as well as the Clarity AD study (Study 301) and its LTE study. Modeling simulations predict that transitioning to once every four weeks maintenance dosing after 18 months of once every two weeks treatment will maintain clinical and biomarker benefits of therapy. AD is a progressive, relentless disease caused by a continuous underlying neurotoxic process that begins before and continues after plaque removal.1,2,3 Only LEQEMBI works to fight AD in two ways: continuously clearing protofibrils and rapidly clearing plaque. This is important because with continuous administration, LEQEMBI clears highly toxic protofibrils* which can continue to cause neuronal injury even after the amyloid-beta (Aβ) plaque has been cleared from the brain.Importance of Ongoing TreatmentData from the off-treatment period between the Study 201 (Phase 2) core study and LTE showed that discontinuation of treatment is associated with reaccumulation of amyloid PET and plasma and CSF biomarkers, and reversion to placebo rate of clinical decline.4For maintenance treatment, once every four weeks dosing regimen may be easier than once every two weeks dosing for patients and care partners to continue treatment for early AD.Ongoing treatment can slow disease progression and prolong the benefit of therapy,4 with the goal of helping patients maintain who they are for longer.In the Clarity AD core study (18 months), the mean change from baseline between the once every two weeks lecanemab treated group and the placebo group was -0.45 (P1 cm, some of which have been fatal, have been observed with this class of medications. Because ARIA-E can cause focal neurologic deficits that can mimic an ischemic stroke, consider whether such symptoms could be due to ARIA-E before giving thrombolytic therapy to a patient being treated with LEQEMBI.Apolipoprotein E ε4 (ApoE ε4) Homozygotes: Patients who are ApoE ε4 homozygotes (~15% of patients with AD) treated with this class of medications have a higher incidence of ARIA, including symptomatic, serious, and severe radiographic ARIA, compared to heterozygotes and noncarriers. Testing for ApoE ε4 status should be performed prior to initiation of treatment to inform the risk of developing ARIA. Prior to testing, prescribers should discuss with patients the risk of ARIA across genotypes and the implications of genetic testing results. Prescribers should inform patients that if genotype testing is not performed, they can still be treated with LEQEMBI; however, it cannot be determined if they are ApoE ε4 homozygotes and at higher risk for ARIA.Consider the benefit of LEQEMBI for the treatment of AD and the potential risk of serious ARIA events when deciding to initiate treatment with LEQEMBI.CONTRAINDICATIONLEQEMBI is contraindicated in patients with serious hypersensitivity to lecanemab-irmb or to any of the excipients of LEQEMBI. Reactions have included angioedema and anaphylaxis.WARNINGS AND PRECAUTIONSAMYLOID-RELATED IMAGING ABNORMALITIESMedications in this class, including LEQEMBI, can cause ARIA-E, which can be observed on MRI as brain edema or sulcal effusions, and ARIA-H, which includes microhemorrhage and superficial siderosis. ARIA can occur spontaneously in patients with AD, particularly in patients with MRI findings suggestive of cerebral amyloid angiopathy (CAA), such as pretreatment microhemorrhage or superficial siderosis. ARIA-H generally occurs with ARIA-E. Reported ARIA symptoms may include headache, confusion, visual changes, dizziness, nausea, and gait difficulty. Focal neurologic deficits may also occur. Symptoms usually resolve over time.Incidence of ARIASymptomatic ARIA occurred in 3% and serious ARIA symptoms in 0.7% with LEQEMBI. Clinical ARIA symptoms resolved in 79% of patients during the period of observation. ARIA, including asymptomatic radiographic events, was observed: LEQEMBI, 21%; placebo, 9%. ARIA-E was observed: LEQEMBI, 13%; placebo, 2%. ARIA-H was observed: LEQEMBI, 17%; placebo, 9%. No increase in isolated ARIA-H was observed for LEQEMBI vs placebo.Incidence of ICHICH >1 cm in diameter was reported in 0.7% with LEQEMBI vs 0.1% with placebo. Fatal events of ICH in patients taking LEQEMBI have been observed.Risk Factors of ARIA and ICHApoE ε4 Carrier StatusOf the patients taking LEQEMBI, 16% were ApoE ε4 homozygotes, 53% were heterozygotes, and 31% were noncarriers. With LEQEMBI, ARIA was higher in ApoE ε4 homozygotes (LEQEMBI: 45%; placebo: 22%) than in heterozygotes (LEQEMBI: 19%; placebo: 9%) and noncarriers (LEQEMBI: 13%; placebo: 4%). Symptomatic ARIA-E occurred in 9% of ApoE ε4 homozygotes vs 2% of heterozygotes and 1% of noncarriers. Serious ARIA events occurred in 3% of ApoE ε4 homozygotes and in ~1% of heterozygotes and noncarriers. The recommendations on management of ARIA do not differ between ApoE ε4 carriers and noncarriers.Radiographic Findings of CAANeuroimaging findings that may indicate CAA include evidence of prior ICH, cerebral microhemorrhage, and cortical superficial siderosis. CAA has an increased risk for ICH. The presence of an ApoE ε4 allele is also associated with CAA.The baseline presence of at least 2 microhemorrhages or the presence of at least 1 area of superficial siderosis on MRI, which may be suggestive of CAA, have been identified as risk factors for ARIA. Patients were excluded from Clarity AD for the presence of >4 microhemorrhages and additional findings suggestive of CAA (prior cerebral hemorrhage >1 cm in greatest diameter, superficial siderosis, vasogenic edema) or other lesions (aneurysm, vascular malformation) that could potentially increase the risk of ICH.Concomitant Antithrombotic or Thrombolytic MedicationIn Clarity AD, baseline use of antithrombotic medication (aspirin, other antiplatelets, or anticoagulants) was allowed if the patient was on a stable dose. Most exposures were to aspirin. Antithrombotic medications did not increase the risk of ARIA with LEQEMBI. The incidence of ICH: 0.9% in patients taking LEQEMBI with a concomitant antithrombotic medication vs 0.6% with no antithrombotic and 2.5% in patients taking LEQEMBI with an anticoagulant alone or with antiplatelet medication such as aspirin vs none in patients receiving placebo.Fatal cerebral hemorrhage has occurred in 1 patient taking an anti-amyloid monoclonal antibody in the setting of focal neurologic symptoms of ARIA and the use of a thrombolytic agent.Additional caution should be exercised when considering the administration of antithrombotics or a thrombolytic agent (e.g., tissue plasminogen activator) to a patient already being treated with LEQEMBI. Because ARIA-E can cause focal neurologic deficits that can mimic an ischemic stroke, treating clinicians should consider whether such symptoms could be due to ARIA-E before giving thrombolytic therapy in a patient being treated with LEQEMBI.Caution should be exercised when considering the use of LEQEMBI in patients with factors that indicate an increased risk for ICH and, in particular, patients who need to be on anticoagulant therapy or patients with findings on MRI that are suggestive of CAA.Radiographic Severity With LEQEMBIMost ARIA-E radiographic events occurred within the first 7 doses, although ARIA can occur at any time, and patients can have >1 episode. Maximum radiographic severity of ARIA-E with LEQEMBI was mild in 4%, moderate in 7%, and severe in 1% of patients. Resolution on MRI occurred in 52% of ARIA-E patients by 12 weeks, 81% by 17 weeks, and 100% overall after detection. Maximum radiographic severity of ARIA-H microhemorrhage with LEQEMBI was mild in 9%, moderate in 2%, and severe in 3% of patients; superficial siderosis was mild in 4%, moderate in 1%, and severe in 0.4% of patients. With LEQEMBI, the rate of severe radiographic ARIA-E was highest in ApoE ε4 homozygotes (5%) vs heterozygotes (0.4%) or noncarriers (0%). With LEQEMBI, the rate of severe radiographic ARIA-H was highest in ApoE ε4 homozygotes (13.5%) vs heterozygotes (2.1%) or noncarriers (1.1%).Monitoring and Dose Management GuidelinesBaseline brain MRI and periodic monitoring with MRI are recommended. Enhanced clinical vigilance for ARIA is recommended during the first 14 weeks of treatment. Depending on ARIA-E and ARIA-H clinical symptoms and radiographic severity, use clinical judgment when considering whether to continue dosing or to temporarily or permanently discontinue LEQEMBI. If a patient experiences ARIA symptoms, clinical evaluation should be performed, including MRI if indicated. If ARIA is observed on MRI, careful clinical evaluation should be performed prior to continuing treatment.HYPERSENSITIVITY REACTIONSHypersensitivity reactions, including angioedema, bronchospasm, and anaphylaxis, have occurred with LEQEMBI. Promptly discontinue the infusion upon the first observation of any signs or symptoms consistent with a hypersensitivity reaction and initiate appropriate therapy. INFUSION-RELATED REACTIONS (IRRs)IRRs were observed—LEQEMBI: 26%; placebo: 7%—and most cases with LEQEMBI (75%) occurred with the first infusion. IRRs were mostly mild (69%) or moderate (28%). Symptoms included fever and flu-like symptoms (chills, generalized aches, feeling shaky, and joint pain), nausea, vomiting, hypotension, hypertension, and oxygen desaturation.In the event of an IRR, the infusion rate may be reduced or discontinued, and appropriate therapy initiated as clinically indicated. Consider prophylactic treatment prior to future infusions with antihistamines, acetaminophen, nonsteroidal anti-inflammatory drugs, or corticosteroids.ADVERSE REACTIONSThe most common adverse reactions reported in ≥5% with LEQEMBI and ≥2% higher than placebo were IRRs (LEQEMBI: 26%; placebo: 7%), ARIA-H (LEQEMBI: 14%; placebo: 8%), ARIA-E (LEQEMBI: 13%; placebo: 2%), headache (LEQEMBI: 11%; placebo: 8%), superficial siderosis of central nervous system (LEQEMBI: 6%; placebo: 3%), rash (LEQEMBI: 6%; placebo: 4%), and nausea/vomiting (LEQEMBI: 6%; placebo: 4%).Please see full Prescribing Informationincluding Boxed WARNING.About lecanemab (LEQEMBI®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab is approved in the U.S.,7 Japan,8 China,9 South Korea,10 Hong Kong,11 Israel,12 the United Arab Emirates,13 the United Kingdom,14 Mexico,15 and Macau. In November 2024, the treatment received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending approval. Eisai has submitted applications for approval of lecanemab in 17 countries and regions.LEQEMBI’s approvals in these countries was based on Phase 3 data from Eisai’s, global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results. The primary endpoint was the global cognitive and functional scale, Clinical Dementia Rating Sum of Boxes (CDR-SB). In the Clarity AD clinical trial, treatment with lecanemab reduced clinical decline on CDR-SB by 27% at 18 months compared to placebo.16,17 The mean CDR-SB score at baseline was approximately 3.2 in both groups. The adjusted least-squares mean change from baseline at 18 months was 1.21 with lecanemab and 1.66 with placebo (difference, −0.45; 95% confidence interval [CI], −0.67 to −0.23; P

TOKYO, Jan 27, 2025 - (JCN Newswire via SeaPRwire.com) - Sébastien Ogier has claimed a record-extending 10th victory on the legendary Rallye Monte-Carlo as TOYOTA GAZOO Racing World Rally Team scored a one-two finish to launch its 2025 FIA World Rally Championship campaign with a maximum points haul.The victory is Ogier’s third Rallye Monte-Carlo win with TGR-WRT and his second with co-driver Vincent Landais, and brings Toyota’s all-time record on the event to six wins.As usual the rally brought a wide range of changeable conditions during the weekend, with dry asphalt stages in the mountains of the French Alps also featuring sections of ice as well as plenty of mud and gravel being dragged onto the road. It provided a challenging first event for the teams and drivers with the revised technical package for 2025, with the top class of Rally1 cars no longer featuring hybrid units and also running on Hankook tyres for the first time.Despite these challenges, the battle for victory remained tight throughout the weekend and went down to the very last stage across the iconic Col de Turini on Sunday afternoon. Ogier had eked out a lead of 20.3 seconds over Evans going into the final day, with the Hyundai pair of Adrien Fourmaux and Ott Tänak also close behind, but an early start combined with cold and wet conditions made for a difficult last tyre choice.Ogier and Evans both took a package of four studded winter tyres plus two supersoft slick tyres, which paid off in the icy first stage prior to sunrise. With the four studded tyres fitted they were around 20s quicker than Fourmaux, but that advantage swung the other way on a drier second stage, where Fourmaux could fit his four slicks and close back to within 4s of Evans and 22.2s of Ogier.The rally-ending Power Stage featured a true mix of conditions, with a largely dry ascent and descent but with some ice atop the famous Col. In the end, all of the top three drivers opted for a mix of slick and studded tyres and it was Ogier who set the best time, just 0.215s quicker than Evans – who ran wide and brushed a bank on the rapid descent to the finish.Ogier’s win is also his 15th for TGR-WRT, drawing him level with team-mate Kalle Rovanperä and their fellow two-time champion Carlos Sainz as the drivers who have achieved the most WRC victories for Toyota.Evans and co-driver Scott Martin start their season strongly, also topping the Super Sunday classification to earn five extra bonus points. 1.1s in front of Rovanperä and 1.8s in front of Ogier.With a different tyre strategy, Rovanperä and Jonne Halttunen were consistent across all conditions on the final day and beat Ott Tänak to fourth overall, securing a solid haul of 18 points from a challenging weekend.Takamoto Katsuta and Sami Pajari built their confidence and pace through the rally. Katsuta won a stage and was third-quickest across Saturday, while Pajari gathered valuable experience on his first Rallye Monte-Carlo in Rally1 machinery. Starting the final day sixth and seventh, both would unfortunately slide off the road in Sunday’s first stage.Quotes:Akio Toyoda (TGR-WRT Chairman)We were able to kick off the 2025 season with Seb's memorable 10th victory in Monte Carlo. Up until 2019, Seb had a streak of six consecutive wins in Monte Carlo with various teams. Since joining Toyota in 2020, he has alternated between 2nd and 1st place every other year. Given this pattern, I was certain that he would win this year. Seb, congratulations on your 10th win in Monte Carlo! I think it's time for you to break that pattern and win again next year!Last season was incredibly enjoyable, as we battled with Hyundai all the way to the final stage of the final round. However, that was just how I felt as a rally fan. As a team member, there were many moments that were quite tough throughout the season. This year, I want to make it a season that we can enjoy from the bottom of our hearts also as team members. And I want to experience that feeling again at Rally Japan! I believe Jari-Matti, Juha, all the drivers, all the co-drivers, and everyone in the team will make it happen! And just so you know, this year's Rally Japan is not the final event...Quotes:Jari-Matti Latvala (Team Principal)“I’m really delighted. We could not really have had a better start to the season than this: we got the maximum 60 points as a team, a one-two-four overall and the 10th victory for Sébastien Ogier on Rallye Monte-Carlo, which is a truly amazing and unique achievement. The conditions were very difficult until the end and the tyre choice was stressful this morning because the road was freezing after the route-note crews had passed through. Unfortunately Sami and Taka went off, and perhaps I should have pushed them to take a safer choice, but this rally was all about the experience for them. With our other drivers it worked out well in the end, so thank you to them. At the same time it was a very entertaining rally and I think we have an exciting season ahead.”Elfyn Evans (Driver car 33)“This was a typical Rallye Monte-Carlo, a bit more extreme than in recent years and it was a properly challenging weekend. I’m very happy to be here at the end with a decent haul of points. Today started off with some very tricky conditions, we made a change at the last moment to take four studded tyres and I wasn’t sure it was the right call. In the end it seems there wasn’t a lot between the two choices and we had a pretty thrilling Power Stage to finish: we had a close moment a few corners from the end but thankfully we managed to get away with it.”Kalle Rovanperä (Driver car 69)“Rallye Monte-Carlo is always tough and it was especially so this year. For me personally it was a pretty difficult weekend. We didn’t have the result that we wanted or the pace that we wanted but we have to be happy at the end to have got some pretty good points. Today was not a bad day for us: we just tried our best, kept consistent and it paid off. A big thanks to the team, now let’s see what we can do in Sweden.”Sébastien Ogier (Driver car 17)“It’s amazing to win this rally for the 10th time: it makes me incredibly happy and proud. This rally is the one that gave me the dream to be a rally driver, so if I could pick only one to win in a season, it would always be this one. This year it’s been a huge fight up until the very last stage. We had changing conditions, difficult tyre decisions and pressure right until the end so I’m glad we managed to keep it under control. We definitely had some moments but to win this rally I think you always need a bit of luck too. It’s a perfect start to the year for the team so we couldn’t ask for anything more.”Takamoto Katsuta (Driver car 18)“This morning in the first stage we knew that the conditions could be quite tricky, but we came to one right-hand corner that was frosty where we didn’t have that information in our pacenotes. We were quite slow going into the corner, but the car went wide and got stuck in a small ditch which we couldn’t get out of. Until then it had been quite a good rally, especially Saturday when the pace was good. It’s a pity but I just need to refocus on the next rally in Sweden and try to do a good job for the team there.”Sami Pajari (Driver car 5)“The approach for today was the same as before and we were not planning to push particularly hard. There was just one surprisingly icy braking point which just caught us out. It was an unfortunate end to our rally, as it been going according to plan until then. On Saturday especially we saw that the times were getting better and the feeling was getting better and the confidence was rising. Everything felt under control so it’s a pity to end the rally like this, but we will try to learn from what happened and look forward to Sweden.”PROVISIONAL FINAL CLASSIFICATION, RALLYE MONTE-CARLO1 Sébastien Ogier/Vincent Landais (Toyota GR YARIS Rally1) 3h19m06.1s2 Elfyn Evans/Scott Martin (Toyota GR YARIS Rally1) +18.5s3 Adrien Fourmaux/Alexandre Coria (Hyundai i20 N Rally1) +26.0s4 Kalle Rovanperä/Jonne Halttunen (Toyota GR YARIS Rally1) +54.3s5 Ott Tänak/Martin Järveoja (Hyundai i20 N Rally1) +59.0s6 Thierry Neuville/Martijn Wydaeghe (Hyundai i20 N Rally1) +5m44.2s7 Josh McErlean/Eoin Treacy (Ford Puma Rally1) +10m15.1s8 Yohan Rossel/Arnaud Dunand (Citroën C3 Rally2) +10m26.8s9 Nikolay Gryazin/Konstantin Aleksandrov (Škoda Fabia RS Rally2) +11m40.7s10 Eric Camilli/Thibault de la Haye (Hyundai i20 N Rally2) +13m14.6sRetired Takamoto Katsuta/Aaron Johnston (Toyota GR YARIS Rally1)Retired Sami Pajari/Marko Salminen (Toyota GR YARIS Rally1)(Results as of 14:30 on Sunday, for the latest results please visit www.wrc.com)2025 FIA World Rally Championship for drivers after round 1:1 Sébastien Ogier 33 points2 Elfyn Evans 263 Adrien Fourmaux 204 Kalle Rovanperä 185 Ott Tänak 116 Thierry Neuville 97 Josh McErlean 68 Yohan Rossel 49 Nikolay Gryazin 210 Eric Camilli 12025 FIA World Rally Championship for manufacturers after round 1:1 TOYOTA GAZOO Racing World Rally Team 60 points2 Hyundai Shell Mobis World Rally Team 363 M-Sport Ford World Rally Team 11What's next?Rally Sweden (February 13-16) is the only full winter event of the season held on snow and ice. Metal studs inserted into the tyres bite into the surface to provide grip and allow for some of the highest speeds of the year. Copyright 2025 JCN Newswire via SeaPRwire.com.

TOKYO, Jan 27, 2025 - (JCN Newswire via SeaPRwire.com) - Anime Tokyo Station is an anime exhibition site focused on Japanese anime content, which has developed a devout fan base even outside Japan. It regularly hosts special exhibitions for popular anime, and attracts over 130,000 visitors a year (as of 2025 January), children and adults alike, from both Japan and overseas.From February 8 to May 6, it will be hosting a special exhibition for the TV anime "OSHI NO KO", which enjoys tremendous popularity among both Japanese and foreign audiences."OSHI NO KO", created by the dream team of Aka Akasaka and Mengo Yokoyari, is a popular anime that uses a novel approach to shine a light on the entertainment industry. It tells the story of the fateful encounter between a young doctor and his favorite idol, Ai, an idol in the group B-KOMACHI. Launched in April 2023, it has drawn a great deal of attention not only for its story but also its music, and last year generated even more buzz with the announcement of a third season.The exhibits in this special exhibition will include key scenes that cover the anime's story, life-sized panels of characters, photo spots, video that lets exhibition attendees experience what it would be like to see a live performance of B-KOMACHI, the idol group from the anime, and more.Come to Anime Tokyo Station and experience the full appeal of "OSHI NO KO".Let’s Enjoy together!! History of Anime Series "OSHI NO KO"- Exhibition OverviewSeason 1 of the TV anime "OSHI NO KO" began airing in April 2023, followed by season 2 in July 2024, becoming popular worldwide. It has now been announced that a third season is being produced. At this exhibition, visitors will be able to experience the world of "OSHI NO KO" and the allure of the idols and other characters that appear in this anime, which was created such a stir.- Highlights of the Exhibition-- ExhibitsScenes from the story so far, life-sized panels of characters-- Photo spotsPhoto spots where you can take photos in the popular "Kana Arima Bell Pepper Exercise" and "Pieyon’s Boot Dance" scenes-- Hands-on areas*B-KOMACHI live show areaEnjoy a simulated experience of a live show by B-KOMACHI, the idol group from the anime*Reproduction of MEMcho's roomMEMcho reacts to you in this reproduction of MEMcho's Room, from her official YouTube channel- DatesFebruary 8 to May 6, 2025Venue Overview- Name: Anime Tokyo Station (also known as "Anime Tokyo") - Location: Floors B1 to 2F of Tokyu East 5 (2-25-5 Minami-Ikebukuro, Toshima-ku, Tokyo)*4 minutes on foot from Ikebukuro Station- Hours: 11:00 a.m. to 7:00 p.m. (last admission: 6:45 p.m.)- Closed: Mondays *If Monday falls on a holiday, the venue will be open on Monday and closed on the following dayNew Year's holiday periodMay be closed on other days Please check the venue website before coming.- Admission fee: Free- Website: https://animetokyo.jpInquiries regarding this press releasePublic Relations Office of "Anime Tokyo Station" (Kyodo PR)Contact person: Miri YasudaE-mail: animetokyo-pr@kyodo-pr.co.jp Press release: https://www.acnnewswire.com/docs/files/20250124.pdf Copyright 2025 JCN Newswire via SeaPRwire.com.

Tokyo and Kawasaki, Japan, Jan 27, 2025 - (JCN Newswire via SeaPRwire.com) - Sustainable Shared Transport Inc. (SST), a subsidiary of Yamato Holdings Co., Ltd. (1) and Fujitsu Limited, today announced the launch of a joint transportation and delivery system for shippers and logistics providers in Japan. SST will start providing the service on February 1, 2025.SST, established on May 21, 2024, aims to build a sustainable supply chain through this platform, which utilizes standardized pallet transportation (physical) and standardized information exchange (digital). This new joint transportation and delivery service, provided by SST, matches shippers and logistics providers on the system, primarily focusing on trunk transport.Fujitsu, recognizing the crucial role of responsible supply chain management in its commitment to developing a digital society, views solving logistics challenges as a key priority within its Materiality. Fujitsu will utilize SST’s joint transportation and delivery service as a shipper and has jointly built a data integration platform with the company. On February 1, 2025, Fujitsu will invest 50 million yen in SST.This initiative comes as the logistics industry in Japan faces various challenges, including transportation capacity shortages and climate change concerns, and all companies are being urged to undergo significant transformations to further improve logistical efficiency and create an attractive work environment. Furthermore, to foster sustainable logistics growth, the Japanese government amended legislation, encouraging shippers and logistics companies to implement logistics optimization measures from April 2025 onwards.However, industry-specific systems, standards, and business practices hinder widespread solutions. To address this task, the Yamato Group established SST in May 2024, fostering open collaboration across industries. Together with Fujitsu, SST has developed a foundational system for data integration across companies.Joint transportation and delivery system and open platform:Creating optimal transport and delivery plans through matching information from shippers and logistics companiesLeveraging the Fujitsu Unified Logistics offering, the system optimizes transportation plans based on shipper data (shipping schedules, packaging, volume) and carrier schedules. Shippers can easily participate in joint transportation and delivery, selecting optimal methods (time slots, transport modes) within standard pallet space units. Logistics providers benefit from increased load factors, reduced empty mileage, and improved driver conditions.Accelerating decision-making and promoting cooperation between companiesThe open platform is compliant with the guidelines established by the Cross-ministerial Strategic Innovation Promotion Program (SIP) Smart Logistics Service project implemented by Japan’s Cabinet Office. This facilitates data integration across industries and companies, enables faster decision-making and fosters collaboration for improved efficiency.Achieving secure data linkage through the blockchainUtilizing Fujitsu's blockchain technology and cybersecurity expertise, the platform prevents unauthorized access and employs data change logging for tamper detection and recovery, ensuring secure data sharing across industries and companies.Trunk transportSST's services enable trunk transportation with scheduled operation, relay transportation, and consolidated transportation in specific regions of Japan, available in standard pallet space units. Additionally, through partnerships with local distribution companies, deliveries within the area will be provided to meet the needs of shippers utilizing the service.Future PlansSST and Fujitsu aim to create a sustainable and cross-industry supply chain by combining Yamato Group's partnerships with approximately 1.7 million corporate clients and over 3,500 logistics providers, its transportation network and operational expertise, and Fujitsu's expertise in manufacturing, distribution, and system development. Furthermore, the two companies will build a digital infrastructure linking commercial and logistics information, and promote data integration with related organizations and platforms to optimize and strengthen the entire supply chain.SST will accelerate joint transportation and delivery by expanding its service area, schedules, and transportation modes to include rail and sea freight in addition to trucking, aiming to expand to 80 routes by the end of March 2026.Fujitsu, under its Fujitsu Uvance business model focused on addressing societal challenges, will continue to contribute to the realization of a physical internet, maximizing transportation, handling, and storage assets through joint transportation and delivery with SST. Furthermore, Fujitsu will collaborate with logistics stakeholders, combining multi-sector open platforms to solve a wide range of cross-industry challenges.Related LinksYamato Holdings press release published on May 21, 2024: “Established a New Company to Provide an Open Platform for Joint Transportation and Delivery to Build a Sustainable Supply Chain.”Fujitsu Unified LogisticsLogistics Information Standards (in Japanese)Material of the press conferenceHeld on January 27, 2025Sustainable supply chain through cross-industry data linkageAbout FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsYamato Holdings Co., Ltd.Corporate Communications StrategyTEL: +81-3-3541-4141 Copyright 2025 JCN Newswire via SeaPRwire.com.